In the realm of scientific exploration, researchers are continuously investigating novel compounds and their potential applications. Among these compounds, DMAA (1,3-dimethylamylamine) and Theacrine have captured the attention of scientists due to their unique properties. It is important to note that the following information is strictly intended for research purposes, and it is not intended to promote human use. With that in mind, let us delve into the intriguing world of DMAA and Theacrine.

DMAA, classified as a neural stimulant, shares a similar structure with amphetamine.[R] It has sparked interest among researchers due to its potential impact on the brain and signaling pathways. On the other hand, Theacrine, an alkaloid structurally resembling caffeine, has also piqued scientific curiosity with its potential to activate similar signaling pathways [R]. While both compounds have been the subject of recent studies, it is crucial to emphasize that their applications are still being explored and must be approached with scientific rigor.

Researchers have turned their attention to the potential cognitive benefits associated with DMAA and Theacrine. Through a combination of clinical studies utilizing both human and animal models, scientists have begun to uncover the promising effects of these compounds on neurocognitive function. These findings lay the foundation for further investigation and open up new avenues of research.

As we embark on this scientific journey, let us remain mindful of the importance of rigorous research, responsible experimentation, and a commitment to furthering our knowledge in a manner that prioritizes the well-being of both humans and animals. The potential insights gained from studying DMAA and Theacrine may contribute to the wider field of neuroscience, offering us a deeper understanding of the intricate workings of the brain.

Key Features

RCD.Bio offers DMAA + pure Theacrine with the following specifications:

  • A purity of 98%, verified by first and third-party laboratory testing.
  • Available in 170mg/20ct/3.4g and 170mg/40ct/6.8g tablet form

How DMAA + Threacrine Works?

1,4 DMAA, a central nervous system stimulant, and theacrine, a compound that interacts with adenosine receptors, work together to provide a potential synergistic effect on concentration and energy. DMAA stimulates the release of neurotransmitters like dopamine and norepinephrine, resulting in a potential improved focus, attentiveness, and alertness. It also acts as a vasoconstrictor, narrowing blood vessels and potentially leads to high blood pressure and increased heart rate, which can give the impression of increased vitality and performance. [R]

On the other hand, research shows that theacrine interacts with the brain’s adenosine receptors, preventing them from suppressing neuronal activity. This interaction leads to a rise in mental and physical energy, an enhanced mood, and improved cognitive performance. Unlike coffee, research shows that theacrine provides these benefits without causing jitters or crashes commonly associated with caffeine consumption.[R]

When DMAA and theacrine are combined, their unique mechanisms of action complement each other. While theacrine impacts adenosine receptors, providing a more sustained and balanced energy boost, DMAA primarily enhances neurotransmitter release. This combination results in improved concentration and increased energy levels.

Please note that the discussion of DMAA and theacrine in this article is solely focused on understanding their working mechanisms and how they can potentially work together. It is important to emphasize that the promotion of these compounds for human consumption is not advocated. 

The scientific basis behind the benefits of DMAA + Threacrine

Only a few clinical research support the following claimed benefits for DMAA. There has to be more proof before these compounds can be used for any of the following uses.

  1. Fat Burning
    A study involving 32 test subjects indicated that DMAA, as part of a dietary supplement, might have contributed to weight loss.  [R] Another study with 12 healthy test subjects suggested that DMAA could potentially promote lipolysis (fat burning) and increase body temperature, potentially aiding in long-term fat loss.[R]
  2. Cognition Benefits
    A trial involving 12 healthy young subjects found that DMAA might have improved cognitive function. The DMAA group exhibited possibly quicker reaction times and performed better on the cognitive-efficiency index compared to the placebo group. [R
  3. LDL Cholesterol Benefits
    Lowering LDL cholesterol is beneficial as high levels increase the risk of heart disease and stroke. In a trial with 25 healthy male subjects, a DMAA-containing supplement appeared to have reduced LDL cholesterol levels by 7 mg/dL, which could be considered statistically significant. [R
  4. Enhancement of Physical Performance
    Preclinical research demonstrated that high dosages of a dietary supplement containing DMAA had the potential to enhance physical performance and tolerance build-up. However, the observed improvement seemed to diminish after four weeks of daily use. [R]

Meanwhile, the potential applications of Theacrine include:

  1. Pain Reduction
    Theacrine has shown promising results in reducing pain sensitivity in a study using mice. Even a low dose of 8mg per kilogram of body weight demonstrated potential analgesic effects. However, further research is needed to determine its effectiveness for pain relief in humans. [R]
  2. Energy Boost
    A single 200mg dose of Theacrine has been associated with increased energy levels, focus, mental clarity, improved motivation during exercise, and libido. [R] It has also shown to enhance physical activity in rats. It is believed to be controlled by the dopamine and adenosine systems. More robust studies are required to confirm these findings. [R]
  3. Mood Improvement
    Theacrine activates dopamine receptors and stimulates the brain’s pleasure and reward center, potentially leading to improved mood and feelings of energy.[R] Combination dietary supplements containing Theacrine and caffeine have shown positive effects on long-lasting energy, mood, and reduction of brain fog and lethargy. [R]
  4. Relaxation Support
    In animal studies, low doses of Theacrine have demonstrated mild sedative and hypnotic effects. [R]
  5. Endurance and Mental Performance
    Theacrine has been studied in test subjects engaged in sports and shown to increase time until exhaustion, indicating improved endurance. When combined with caffeine, Theacrine enhanced endurance even more than either compound alone. [R]


Despite this, this material is being provided for educational reasons only; it is not intended to be taken as medical advice. DMAA + Theacrine is not meant for human consumption and is only meant for use in laboratories and research.

Potential side effects

Theacrine can cause lethargy and drowsiness. Theacrine and sedative medicines together may theoretically cause excessive sleepiness. [R]

Furthermore, animal tests on theacrine’s toxicity revealed no harmful effects when used at the approved doses. [R]

What are the natural sources of Theacrine?

Theacrine is naturally found in coffee, as well as in Cupuacu an exotic fruits, and certain types of tea, specifically Camellia assamica var. kucha. c


DMAA and Theacrine are two compounds that have been studied for their potential benefits. DMAA may acts as a neural experimental stimulants found to release neurotransmitters and increasing focus and alertness. It may also promote fat burning, improve cognitive performance, lower LDL cholesterol levels, and enhance physical performance. 

On the other hand, Theacrine interacts with adenosine receptors in the brain, that may result in increased mental and physical energy, improved mood, pain reduction, relaxation support, and enhanced endurance and mental performance. However, further research is needed to establish the efficacy of these compounds in humans. 

Because DMAA and Theacrine have different modes of action, combining the two can have beneficial effects. The combination may improve concentration, energy, and athletic performance as suggested by animal model studies but further research is needed to confirm the exact mechanism and safety.


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PLEASE NOTE: All products offered by are strictly intended for laboratory and research purposes only. They are not intended for use on animals or humans.