9-Methyl-β-Carboline (9-Me-BC) is a synthetic nootropic that has been studied in animal research. It has demonstrated neuroprotective and anti-inflammatory effects, potentially promoting brain health. Additionally, 9-Me-BC may increase dopamine levels, potentially improving mood.

Furthermore, preclinical studies have suggested that 9-Me-BC has the potential to inhibit the expression of inflammatory cytokines and receptors, further supporting its anti-inflammatory properties.

Animal studies have also indicated that 9-Me-BC exhibits neuro-restorative and neuro-stimulative effects, highlighting its potential to promote brain function and recovery.

Even though 9-Me-BC could potentially provide the above-mentioned benefits, it is still described as a research chemical. Buy 9 Me-BC for research purposes only.

9 Me BC Product Details

9-Me-BC is a derivative of β-Carboline (BC) with a half-life of approximately 15-24 hours. It may even function as an MOA-B inhibitor. BCs are naturally occurring alkaloids found in fruits, fish, and beef, as well as in the human brain, blood, and cerebrospinal fluid.

One of the notable properties of 9-Me-BC is its ability to inhibit the enzymes monoamine oxidase A and B, which are responsible for removing neurotransmitters like norepinephrine, dopamine, and serotonin from the brain. By potentially preventing their breakdown, 9-Me-BC may contribute to mood elevation.

In addition, 9-Me-BC powder has shown promising effects in vivo, including increasing hippocampal dopamine levels, promoting dendrite outgrowth, and enhancing spatial learning performance. It has also demonstrated restorative effects in an animal model of Parkinson’s disease.

  • CAS Number 2521-07-5
  • Molar Mass 182.226 g·mol−1
  • Chemical Structure C12H10N2
  • IUPAC Name 5-Methyl-5H-pyrido[3,4-b]indole

Key Features of 9-Me-BC 

  • 98% Purity
  • 500mg | 1000mg
  • Sold for research purposes only

Potential Benefits of 9-Me-BC

What follows is a summary of the existing clinical, animal, and cell-based research on 9-Me-BC. The information in this section is for educational purposes only and does not constitute medical advice. All clinical research must be conducted with the oversight of the appropriate institutional review board and appropriate institutional animal care to ensure that the studies do not violate the animal welfare act.

9-Me-BC and Inflammation

Cell-based studies have demonstrated that 9-Me-BC treatment potentially prevents toxin-induced microglia proliferation and promotes an anti-inflammatory environment by decreasing the expression of inflammatory cytokines and receptors. Furthermore, 9-Me-BC has been found to reduce the expression of inflammation-related genes involved in both inflammation and programmed cell death. [R] [R]

9-Me-BC and Cognitive Enhancement

Animal studies have indicated that 9-Me-BC treatment may enhance cognitive function, particularly in tasks dependent on the hippocampus. This improvement is thought to be linked to elevated levels of dopamine in the hippocampus, as well as increased dendritic and synaptic proliferation. The observed enhancement in spatial learning further supports the relationship between increased dopamine levels and improved cognitive performance. [R]

9-Me-BC and Mitochondrial Respiratory Chain

Preclinical studies indicate that 9-Me-BC may improve the mitochondrial respiratory chain (MRC), which is essential for ATP production. Dysfunction of the MRC can lead to increased production of reactive oxygen species (ROS). Although studies indicate that 9-Me-BC may enhance ATP production and bodily functions by improving the MRC, further clinical investigations are necessary to fully understand its effects in this regard. [R]

9-Me-BC and Neuroprotection

Studies conducted on cells have revealed several neuroprotective actions of 9-Me-BC. It has been shown to inhibit the release of lactate dehydrogenase, increase ATP content, and reduce the expression of inflammation-related genes. Moreover, 9-Me-BC inhibits the activity of monoamine oxidase enzymes, which may contribute to its ability to increase dopamine levels and inhibit apoptosis in cell cultures. [R] [R]

9-Me-BC and Parkinson’s Disease

In animal models of Parkinson’s disease, 9-Me-BC has demonstrated potential restorative effects. It may improve the expression and transcription of neurotrophin-related genes that are typically reduced in Parkinson’s patients. Additionally, 9-Me-BC has shown the ability to stimulate, regenerate, and protect dopaminergic neurons, while inhibiting monoamine oxidase A and B. These findings suggest that 9-Me-BC could be a promising compound for the treatment of Parkinson’s disease. [R] [R]

How It Works

While the precise mechanism of action of 9-Me-BC is not fully understood, research suggests several actions associated with this compound. It has been found to inhibit monoamine oxidases A and B, which could potentially elevate the levels of various neurotransmitters in the brain. Additionally, 9-Me-BC has shown the potential in reducing the activity of inflammatory cytokines in the brain, contributing to its anti-inflammatory effects.

In animal studies, 9-Me-BC has demonstrated the potential to promote the growth of dopaminergic neurons in the hippocampus, enhance dendrite outgrowth, and improve spatial learning performance. These effects indicate its potential neuroprotective and cognitive-enhancing properties in vivo.

Moreover, in an animal model of Parkinson’s disease, 9-Me-BC has exhibited restorative effects, suggesting its potential therapeutic value in neurodegenerative conditions.

Although these findings provide valuable insights into the actions of 9-Me-BC, further research is needed to fully elucidate its exact mechanism of action and its potential applications for human health.


When researching the use of Methyl Beta Carboline 9, it is essential to take certain precautions. Here are some precautions to keep in mind:

Observe best practices for studying research chemicals: Studying research chemicals requires a responsible and informed approach to ensure safety and meaningful scientific exploration. Research chemicals, also known as designer drugs or experimental compounds, are substances synthesized for scientific investigation or exploration of their properties.

Follow recommended dosage: Adhere to the recommended dosage instructions outlined on the product label. Avoid exceeding the suggested dose to minimize the risk of potential adverse effects among test subjects.

Potential Side Effects

The safety profile of 9-Me-BC has not been extensively studied, as it is primarily used in laboratory research and has not been approved for human use. Therefore, its potential side effects and long-term safety remain largely unknown. It is crucial to exercise caution and follow ethical guidelines when handling and researching this compound.

Given its inhibitory effects on monoamine oxidase enzymes, there is a possibility of interactions with other medications or substances that affect neurotransmitter levels. Additionally, individual sensitivity and variations in response to 9-Me-BC may exist, potentially leading to unpredictable effects.

As with any research chemical, it is important to prioritize safety and adhere to proper handling, storage, and usage protocols. Consulting with professionals experienced in laboratory research and following ethical guidelines is essential for the safe handling and investigation of 9-Me-BC.


In conclusion, 9-Methyl β-Carboline (9-Me-BC) shows promise as a valuable compound for laboratory research use in various fields. It has demonstrated potential benefits in preclinical research, including its role as a cognitive enhancer and its effects on hippocampal dopaminergic neurons. However, it is important to emphasize that 9-Me-BC is not intended for human consumption and should only be used in appropriate institutional research settings under the guidance of an institutional review board.

The inhibition of monoamine oxidase B (MOA-B) by 9-Me-BC suggests its potential as a therapeutic agent for neurodegenerative diseases. Additionally, its effects on gene expression, such as increasing the expression of tyrosine hydroxylase and dopamine-related genes, highlight its potential impact on neurotransmitter levels.

It is crucial to note that the information provided in this discussion is for informational purposes only and does not constitute medical advice. Clinical research involving 9-Me-BC is necessary to further evaluate its safety, efficacy, and potential therapeutic applications in humans. Until such research is conducted, caution must be exercised, and 9-Me-BC should not be used for human consumption.


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