Andarine S4


Are you in search of a remarkable research chemical that holds immense potential in the field of research? Look no further, as we introduce you to Andarine S4. Classified as a selective androgen receptor modulator (SARM), Andarine S4 is a chemical renowned for its binding abilities to the androgen receptor, the primary target of testosterone. While we do not promote its human use, Andarine S4 offers exciting possibilities in the realm of scientific experiments and investigation. Originally conceived as a potential treatment for osteoporosis and muscle wasting, [R] Andarine S4 quickly gained attention for its remarkable qualities in preclinical studies. Researchers were captivated by its high oral bioavailability, making it easily accessible within the body of research subjects, and its superior effects on lean muscle and bone structure in animal experiments. [R] These early findings positioned Andarine S4 as an ideal SARM candidate for further exploration.

Beyond its initial focus on osteoporosis and muscle wasting, Andarine S4 sparked interest in other potential applications, including its ability to aid in fat loss. The multifaceted properties of this research chemical make it a subject of great curiosity and promise for scientists and researchers alike.

Key Features

RCD.Bio offers Andarine S4 with the following specifications:

  • A purity of 98%, verified by third-party laboratory testing.
  • Available in liquid and powder form

 How Andarine S4 Works?

Andarine S4 has shown promise in laboratory studies by demonstrating a strong affinity for the androgen receptor (AR). By binding to the AR, Andarine mimics the effects of testosterone, which plays a crucial role in muscle and bone development. What sets Andarine apart from other traditional chemicals is its selective nature, as it primarily targets muscles and bones rather than reproductive organs [R]

Andarine’s mechanism of action revolves around its selective binding to the androgen receptors in muscles and bones. By activating these receptors, it promotes protein synthesis and increases nitrogen retention within muscle cells. This ultimately leads to enhanced muscle growth, improved strength, and increased endurance.

The scientific basis behind the benefits of Andarine

This section reviews clinical and scientific research on Andarine to date. Keep in mind that Andarine’s effects on the human body have not been thoroughly studied. 

Muscle Mass

Originally developed to prevent muscle wasting, Andarine has been shown in animal studies to increase muscle mass and strength in animals.

Administration of Andarine to castrated rats for 4 weeks increased muscle mass as significantly as DHT (dihydrotestosterone). Interestingly, Andarine did not cause the problematic prostate weight gain associated with other traditional chemical use. [R]

However, more research is needed to fully understand the effects of Andarine S4 particularly skeletal muscle and when compared to anabolic steroids

Fat Loss

A notable study has revealed that Andarine S4 SARM has the ability to inhibit the production of a hormone called hormone-sensitive lipase. This hormone plays a crucial role in regulating the metabolism of stored fat in the body. Furthermore, Andarine S4 has demonstrated promising results in reducing body fat in ovariectomized female rats. In addition to improving bone strength, Andarine S4 exhibited a positive effect on body composition by decreasing body fat levels [R] Fat is burned for a large amount of energy levels, which is used to build muscle mass.  

Several studies conducted on animal models, particularly mice, have also cited the fat loss benefits associated with Andarine S4. These studies provide further evidence of Andarine’s potential to enhance fat metabolism and support a more favorable body composition [R1; R2, R3]

Improve Endurance and Strength

Studies conducted on mice have revealed that Andarine S4 holds the potential to increase both endurance and strength. [R]

Reduce Prostate Size

Benign prostatic hypertrophy refers to the non-cancerous enlargement of the prostate gland, typically affecting aging men. The condition can lead to bothersome urinary symptoms such as frequent urination, weak urine flow, and difficulty emptying the bladder. Treating BPH often involves managing symptoms and reducing the size of the prostate gland .While various treatment options exist, researchers have explored the potential of tissue-selective androgen receptor modulators (SARMs) in addressing this condition. 

Andarine S4, a notable SARM, has shown promise in reducing prostate size based on studies conducted in rats. Research suggest Andarine S4, have the potential to suppress androgens and reduce prostate size. [R]

This presents an intriguing avenue for exploring Andarine S4’s role in the treatment of benign prostatic hyperplasia. However, more research is needed to fully understand the effects of Andarine S4 on human subjects. 

Bone Density

S4 also prevented ovariectomy-induced bone loss in female rat models of osteoporosis. [R]

At a dose of 3 mg/kg/day, Andarine S4 has demonstrated the ability to fully restore bone mineral density and bone strength in rat models. Additionally, it has been found to suppress luteinizing hormone (LH) and follicle-stimulating hormone (FSH), both of which play roles in gonadal function and follicular growth. The restoration of bone density and strength, combined with the hormonal effects, suggests the potential of Andarine S4 in promoting bone health [R]

In an ovariectomized rat model of post-menopausal osteoporosis, Andarine S4 has also exhibited positive effects on bone quality. By enhancing bone quality, Andarine S4 may contribute to improved structural integrity and reduced fracture risk in individuals susceptible to osteoporosis  [R


Andarine is an unapproved drug with completely unknown side effects. SARMs are believed to have fewer side effects than other traditional chemicals. However, this claim has not yet been proven.

Keep in mind that SARMs like Andarine have not undergone proper clinical trials. In fact, SARMs may pose more risks than many other substances (including other traditional chemicals and testosterone). 

Furthermore, this material is being provided for educational reasons only; it is not intended to be taken as medical advice. Andarine S4  is not meant for human consumption and is only meant for use in laboratories and research.

Potential side effects

In both men and women, LH (luteinizing hormone) and FSH (follicle stimulating hormone) stimulate the production of reproductive hormones. However, suppressing these two hormones can interfere with normal estrogen/testosterone levels. Andarin suppressed LH and FSH hormones in castrated rats when castration increased these hormones. However, it did not affect normal male rats.  [R]

Vision impairment is the most serious problem and the most well-known side effect of taking Andarine. The S4 molecule binds to the androgen receptors (acting as a full androgen receptor agonist) in the eye, giving it a yellowish tint within a short period of time. This usually happens at night, especially when moving from dark to bright areas. [R]

Claims of Andarine S4 causing water retention as a side effect ,contrary to common beliefs, there is no scientific evidence supporting it.

What is the half-life of S4 Andarine?

The half-life of S4 Andarine is roughly 4 hours. [R]

Where Can I Buy the Best S4 for sale? offers S4 Andarine for sale online.

When buying S4 Andarine, it is important to choose a reputable seller who provides quality products. At, each product is accompanied by a third-party-issued Certificate of Analysis showing identification, purity, and concentration of our product. Offering fast shipping worldwide!


Andarine S4 is a selective androgen receptor modulator (SARM) that was originally developed to treat osteoporosis and muscle wasting. It binds to the androgen receptor, mimicking the effects of testosterone, but with a stronger effect on muscles and bones and fewer side effects on reproductive organs. Studies on animals suggest that Andarine may increase muscle mass, reduce body fat, improve endurance and strength, reduce prostate size, and prevent bone loss. However, there are no thorough studies on humans, and the use of Andarine is not approved for human consumption. Potential side effects include the suppression of LH and FSH hormones and vision impairment.


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PLEASE NOTE: All products offered by are strictly intended for laboratory research use purposes only. They are not intended for use on animals or humans.