Centrophenoxine is a cholinergic nootropic that has shown promising results in various clinical studies. Centrophenoxine powder has been found to potentially enhance memory in both healthy elderly test subjects and older clinical subjects with dementia, indicating it could provide cognitive benefits.

Moreover, Centrophenoxine has demonstrated potential neuroprotective effects in animal studies. It may help shield nerve cells from oxidative damage resulting from stroke or toxic exposure, suggesting its therapeutic potential in mitigating neurological conditions.

Furthermore, Centrophenoxine has been found to have positive effects on neuronal functioning. It exhibits the potential to increase RNA synthesis, glucose uptake, and protein synthesis in neurons, which are crucial processes for optimal brain function.

Regardless of the supposed Centrophenoxine benefits, it is still categorized as a research chemical. Due to this fact, buy Centrophenoxine capsules for laboratory research use alone.

Centrophenoxine Product Details

Meclofenoxate, commonly known as centrophenoxine, is a cholinergic nootropic with the potential to improve cognition. By addressing the decreased quantity of acetylcholine levels in the brain, Centrophenoxine has the potential to positively impact crucial functions such as learning and memory.

Originally developed in 1959 in France, Centrophenoxine was initially explored as a treatment for age-related brain disorders, particularly dementia. Clinical research has indicated that Centrophenoxine may offer benefits for test subjects with medium-level dementias, particularly in older age groups.

In preclinical studies, Centrophenoxine has demonstrated its potential to protect nerve cells from oxidative damage. It exhibits antioxidant properties by reducing the damage caused by free radicals and increasing the activity of major antioxidants in the brain. Additionally, Centrophenoxine may enhance energy utilization in brain cells, further supporting optimal brain function.

These findings suggest that Centrophenoxine has neuroprotective properties and may contribute to improved cognitive health. Further research is necessary to better understand its mechanisms of action and explore its potential applications in treating age-related cognitive decline and other neurological disorders.

  • CAS Number 51-68-3
  • Molar Mass 257.71 g·mol−1
  • Chemical Formula C12H16ClNO3
  • IUPAC Name 2-Dimethylaminoethyl (4-chlorophenoxy)acetate

Key Features of Centrophenoxine for Sale

  • 98% Purity
  • 25g
  • Sold for research purposes only

Potential Benefits of Centrophenoxine

Centrophenoxine and Learning & Memory Enhancement

Clinical and preclinical studies have indicated the positive effects of Centrophenoxine on learning and memory. In a certain study involving healthy elderly test subjects, Centrophenoxine treatment potentially facilitated the formation of long-term memories and increased mental alertness. [R]

Other laboratory-controlled studies with animals demonstrated that animal subjects treated with Centrophenoxine learned tasks more efficiently and exhibited improved memory. In old mice, Centrophenoxine significantly enhanced memory after three months of treatment. [R]

Centrophenoxine and Neuroprotection

Preclinical studies have shown that Centrophenoxine has potential neuroprotective properties. It increases the activity of antioxidants in the brain, suggesting its potential effectiveness in combating oxidative stress conditions in the aging brain. Another study revealed that Centrophenoxine potentially reduced the accumulation of lipofuscin, the age pigment, and had positive effects on cell metabolic functions. It also delayed the aging process of glial cells. [R] [R] [R]

Furthermore, when administered to rats with various types of brain injury, Centrophenoxine prevented cognitive deficits associated with elevated oxidative stress, improving memory, motor control, and overall cognitive function.

Centrophenoxine and Dementia

Several trials have investigated the effects of Centrophenoxine on dementia patients. In a double-blind placebo-controlled trial, Centrophenoxine treatment showed potential for improving memory functions in 48% of elderly dementia clinical subjects, compared to 28% in the placebo group. Another trial involving elderly test subjects with senile dementia of Alzheimer’s type (SDAT) found that prolonged treatment with Centrophenoxine and another synthetic compound potentially enhanced cognitive performance, including attention, concentration, memory, and IQ. [R] [R]

Additionally, a double-blind pilot trial focusing on older patients with mild-to-moderate degrees of dementia demonstrated that the Centrophenoxine group displayed improvements in all key metrics compared to the control group. [R]

Centrophenoxine and Lifespan

Animal studies have suggested that Centrophenoxine may have an impact on lifespan. One study showed that treated mice had an increased lifespan of up to 40%. Centrophenoxine was found to reduce the activity of substances associated with aging, including lipofuscin pigments, lysosomal enzymes, acid phosphatase, and simple esterase. Another animal study indicated that Centrophenoxine potentially reversed the effects of brain aging by reducing lipofuscin concentration and lipid peroxidation. [R] [R]

How It Works

Dimethyl-aminoethanol (DMAE) and parachlorphenoxyacetic acid (pCPA) are the two chemical substances that make up centrophenoxine. DMAE, a natural substance found in certain foods and in small amounts in the brain, serves as the primary active ingredient in this compound.

Upon potential absorption in the human body, Centrophenoxine has the potential to break down into DMAE and pCPA. The residual Centrophenoxine may potentially circulate in the bloodstream while the DMAE apparently transforms into choline before crossing the blood-brain barrier.

Centrophenoxine exerts its effects through several proposed mechanisms of action. Firstly, it has the potential to increase acetylcholine levels in the brain, a neurotransmitter crucial for functions such as muscle contraction, heart rate regulation, and memory and learning processes.

Secondly, Centrophenoxine may enhance glucose uptake in the brain, providing more energy and improving blood flow, thus ensuring an adequate oxygen supply to the brain and neurons. Additionally, the compound has the potential to enhance RNA production by stimulating protein turnover in neurons, particularly in areas where damaged proteins can be replaced. Lastly, Centrophenoxine shows promise in reducing lipofuscin levels, the aging pigment that accumulates in cells, including neurons, and is responsible for the formation of brown liver spots on the skin.

Animal studies have indicated that Centrophenoxine may be effective in decreasing lipofuscin concentrations. These various mechanisms of action highlight the potential cognitive benefits and neuroprotective properties of Centrophenoxine, though further research is necessary to fully understand its effectiveness and explore its potential applications in brain health and age-related cognitive decline.


When researching the use of Centrophenoxine, it is essential to take certain precautions. Here are some precautions to keep in mind:

Observe best practices for studying research chemicals: Studying research chemicals requires a responsible and informed approach to ensure safety and meaningful scientific exploration. Research chemicals, also known as designer drugs or experimental compounds, are substances synthesized for scientific investigation or exploration of their properties.

Follow recommended dosage: Adhere to the recommended dosage instructions outlined on the product label. Avoid exceeding the suggested dose to minimize the risk of potential adverse effects among test subjects.

Potential Side Effects

Centrophenoxine could lead to certain adverse reactions such as nausea, headaches, dizziness, gastrointestinal problems, and modest stimulant effects that might interfere with sleep if used late in the day.


In conclusion, Centrophenoxine capsules have shown potential benefits in improving cognitive function and addressing age-related brain aging. This nootropic compound, with its ability to cross the blood-brain barrier, has demonstrated its effectiveness in enhancing memory and other cognitive functions. By increasing the number of essential neurotransmitters and stimulating RNA production, Centrophenoxine may contribute to improved cognitive performance.

It is crucial to note that appropriate handling methods and dosage guidelines should be followed when using Centrophenoxine. While laboratory research has provided valuable insights into its potential applications, further evaluation is needed to fully understand its effects and determine its suitability for specific conditions.

In summary, Centrophenoxine offers potential advantages in supporting cognitive functions and addressing age-related brain aging. While it may contribute to memory enhancement and cognitive improvement, its effects should be evaluated within a holistic approach to brain health.


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PLEASE NOTE: All products offered by are strictly intended for laboratory and research purposes only. They are not intended for use on animals or humans.