DHEA Dehydroepiandrosterone


The adrenal glands play a crucial role in the production of a hormone called dehydroepiandrosterone (DHEA), which serves as a precursor for both male and female sex hormones, namely androgens and estrogens. However, as the human body ages, DHEA levels begin to gradually decline after reaching their peak around the age of 25. This decline has prompted extensive research into the potential of DHEA as a prescription drug for maintaining balanced hormone levels.

Given that DHEA levels decrease with age, researchers have explored whether DHEA could serve as an effective anti-aging solution or dietary supplement. These findings have further fueled the interest of researchers in investigating the potential benefits of DHEA food supplements in addressing these conditions.

It is important to emphasize that DHEA is not an approved form of medication which means you should only purchase it for research purposes.

DHEA Dehydroepiandrosterone Product Details

DHEA (Dehydroepiandrosterone) is a naturally occurring hormone in the human body. It is produced by the adrenal glands and plays a crucial role in the synthesis of other hormones, including testosterone and estrogen.

DHEA supplements are available in the form of oral capsules or tablets. These supplements are commonly marketed for their potential benefits in various areas, including aging, cognition, sexual health, and overall well-being. However, it’s important to note that the efficacy and safety of DHEA supplementation for these purposes are still subjects of ongoing research and debate.

  • CAS Number 53-43-0
  • Molar Mass 288.484 g/mol
  • Chemical Formula C19H28O2
  • IUPAC Name (3S,8R,9S,10R,13S,14S)-3-hydroxy-10,13-dimethyl-1,2,3,4,7,8,9,11,12,14,15,16-dodecahydrocyclopenta[a]phenanthren-17-one

Key Features of DHEA Dehydroepiandrosterone

  • 98% Purity
  • 3g | 6g
  • Sold for research purposes only

Potential Benefits of DHEA Dehydroepiandrosterone

DHEA on Adrenal Glands

The adrenal glands are one of the primary sources of DHEA in the body. Adrenal insufficiency is a condition where the adrenal glands do not produce adequate levels of hormones. This can lead to symptoms such as weakness, fatigue, and fluctuations in blood pressure. DHEA supplements have been investigated as a possible treatment for symptoms of adrenal insufficiency. Some studies suggest that DHEA supplementation may improve the quality of life for individuals with these symptoms.  [R] [R] [R]

DHEA on Bone Density

Numerous studies have indicated that as individuals age, there is a decline in bone density associated with decreased levels of DHEA. A recent study focused on DHEA replacement therapy in older adults, which revealed promising results. In the DHEA group, women showed a significant increase in spine bone mineral density (BMD) of 1.7% during the first year and 3.6% after two years of supplementation. [R] [R]

In contrast, the placebo group’s spine BMD remained constant in the first year but increased by 2.6% above baseline after switching to DHEA in the second year. These findings suggest a potential role for DHEA in improving bone density in older individuals. [R]

DHEA and Erectile Dysfunction

Preliminary evidence suggests that DHEA may assist individuals with erectile dysfunction (ED) in achieving and maintaining erections. This effect may be due to DHEA being converted into testosterone in the body. However, more research is needed to establish the effectiveness of DHEA in treating ED. [R]

DHEA and Fat Burning

Studies have explored the effects of DHEA on fat mass and have shown modest reductions in fat mass, particularly in patients with adrenal gland issues. DHEA supplements may potentially produce small decreases in fat mass in elderly men or adults with suboptimal adrenal gland function. [R]

Additionally, a compound called 7-keto DHEA has shown promise in promoting fat burning when combined with moderate exercise and a reduced-calorie diet. Research has demonstrated that 7-keto DHEA, in conjunction with lifestyle modifications, significantly reduced body weight and body fat compared to diet and exercise alone. [R][R]

DHEA and Depression

A review of studies examining the effects of DHEA in the treatment of depression and depressive symptoms suggests that DHEA may have potential effectiveness, particularly in cases of minor depression or when conventional medication is not effective. Further research is needed to fully understand the role of DHEA in treating depression. [R]

DHEA on Muscle Mass

A recent study investigated the effects of DHEA on muscle mass and strength in elderly individuals. The study involved a 10-month DHEA replacement therapy, with the addition of weightlifting exercise training during the last 4 months. The results showed that DHEA alone for 6 months did not significantly increase strength or muscle volume. However, when combined with 4 months of weightlifting training, DHEA therapy enhanced the effects on muscle strength and volume. [R]

Measurements using one-repetition maximum and Cybex dynamometry indicated increased muscle strength, while magnetic resonance imaging showed an increase in muscle volume. [R]

The study also observed an increase in serum insulin-like growth factor concentration in response to DHEA replacement, suggesting a potential beneficial effect on muscle mass and strength in response to heavy resistance exercise in elderly individuals. [R]

DHEA on Sexual Function

Given that DHEA can modulate male and female sex hormones, it can also affect sexual performance. Research has shown that DHEA therapy improved outcomes in in-vitro fertilization (IVF) for women with fertility issues. Compared to prior treatment, women undergoing DHEA therapy produced more eggs, and a higher percentage of those eggs were successfully fertilized. These findings indicate a potential positive impact of DHEA on sexual function and fertility. [R]

How It Works

The exact mechanism of action of dehydroepiandrosterone (DHEA) is not fully understood. However, it is thought to exert its effects on the body via multiple pathways.

DHEA is a precursor hormone, meaning that it can be converted into other hormones such as testosterone and estrogen in various tissues. Once synthesized, these hormones can bind to specific receptors and exert their biological effects.

DHEA itself can also directly bind to and activate certain receptors, such as the androgen receptor and estrogen receptor. By interacting with these receptors, DHEA can modulate gene expression and affect various physiological processes.

Moreover, DHEA has been found to influence the production and release of other hormones and growth factors in the body. For example, it has been shown to stimulate the release of insulin-like growth factor 1 (IGF-1), which plays a role in promoting growth and maintaining tissue integrity.

Additionally, DHEA has antioxidant properties and may help reduce oxidative stress and inflammation in the body. It may also affect neurotransmitter systems in the brain, potentially influencing mood and cognitive function.

It is important to note that the mechanisms of action of DHEA are complex and may vary depending on the specific tissue or system being studied.


When researching the use of DHEA Dehydroepiandrosterone, it is essential to take certain precautions. Here are some precautions to keep in mind:

Observe best practices for studying research chemicals: Studying research chemicals requires a responsible and informed approach to ensure safety and meaningful scientific exploration. Research chemicals, also known as designer drugs or experimental compounds, are substances synthesized for scientific investigation or exploration of their properties.

Follow recommended dosage: Adhere to the recommended dosage instructions outlined on the product label. Avoid exceeding the suggested dose to minimize the risk of potential adverse effects among test subjects.

Potential Side Effects

The long-term safety of DHEA has not been extensively studied, leaving uncertainties regarding its potential risks and benefits over extended periods of use.

Test subjects with hormone-related malignancies, such as breast, prostate, ovarian, adrenal, and testicular cancer, or those with a family history of these diseases, should exercise caution and avoid DHEA. The reason is that DHEA can potentially be converted by the body into estrogen and testosterone, whih may have detrimental effects and adverse health outcomes in individuals with hormone-related cancers.

Additionally, test subjects with severe diabetes should refrain from using DHEA due to potential risks. Research suggests that DHEA supplementation may elevate the risk of bleeding or blood clotting, which can be particularly concerning for patients with diabetes who are already prone to vascular complications. Moreover, DHEA may also have an impact on heart rate, potentially causing rapid heartbeat in some clinical test participants.


In conclusion, DHEA (Dehydroepiandrosterone) supplementation has shown potential benefits across various aspects of health and well-being. As the body’s natural production of DHEA begins to decline with age, supplementing with DHEA can help maintain optimal levels and support overall health.

Research suggests that DHEA supplementation may have positive effects on muscle mass and exercise performance, particularly when combined with resistance training. Furthermore, it may play a role in promoting bone density, which is crucial for maintaining skeletal health as we age.

DHEA has also been evaluated for its potential impact on brain health, mood regulation, and skin conditions like acne. While further studies are needed to fully understand the extent of these benefits, initial findings indicate promising outcomes.


Please take note of the scientific applications of this best-seller product and carefully read our Terms and Conditions before making a purchase from RCD.bio. By completing your order and submitting payment, you agree to abide by our Terms and Conditions. Please be aware that the product packaging may differ slightly from the images displayed on our website.

If for any reason you are not completely satisfied with the product you receive, please contact us at [email protected]. Our team is dedicated to ensuring customer satisfaction and will be happy to assist you.

PLEASE NOTE: All products offered by RCD.bio are strictly intended for laboratory and research purposes only. They are not intended for use on animals or humans.