Evodiamine + Theacrine 


Evodiamine and Theacrine, two natural compounds, have garnered attention for their potential health benefits. Evodiamine, derived from traditional Chinese medicine, is currently under investigation for its ability to boost metabolism and aid in weight management. On the other hand, Theacrine has shown promise in improving concentration and focus, offering an alternative to caffeine without the associated tolerance issues.

The exploration of these compounds in tandem presents an exciting opportunity for synergistic effects, amplifying their individual advantages. By combining Evodiamine and Theacrine, researchers anticipate a potential enhancement of their respective benefits, leading to even more promising outcomes.

However, Evodiamine Theacrine is not an approved dietary supplement. Buy this research chemical for research purposes only.

Evodiamine + Theacrine Product Details


Evodiamine, a natural compound deeply rooted in traditional Chinese medicine, has garnered significant attention for its potential as a weight loss aid. With centuries of historical usage, its recent exploration has unveiled its ability to potentially suppress appetite and elevate metabolic rates, offering promising prospects in the realm of weight management.

Characterized by the chemical formula C19H17N3O and the CAS number 518-17-2, evodiamine has become a subject of scientific curiosity. While research on its weight loss properties is still in its early stages, preliminary studies suggest that it may effectively contribute to reducing body weight, BMI, and fat accumulation.

Beyond its potential impact to burn fat leading to weight loss, evodiamine has also exhibited other intriguing health benefits. It showcases anti-inflammatory properties that can assist in combating inflammation, and it holds neuroprotective potential, safeguarding the nervous system from harm.

As researchers delve deeper into the realm of evodiamine, further insights into its multifaceted benefits and mechanisms of action are anticipated, holding promise for both weight management and overall well-being.


Theacrine, a natural compound bearing structural similarities to caffeine, has the potential to enhance motivation and mental focus, all while circumventing the tolerance-forming effects commonly associated with caffeine consumption.

Emerging research indicates that Theacrine may play a role in bolstering energy levels, supporting sustained focus, and mitigating fatigue, presenting a compelling array of potential benefits.

The chemical formula of Theacrine is C9H12N4O3, with a molar mass of 224.22 g/mol. Recognized under the IUPAC name 1,3,7,9-tetramethyluric acid, it bears a CAS number of 2309-49-1.

As scientific exploration advances, deeper insights into Theacrine’s mechanisms of action and its diverse range of effects are anticipated, holding promise for those seeking heightened mental performance and sustained vitality.

Key Features of Evodiamine + Theacrine 

  • 98% Purity
  • 150mg/20ct/3g | 150mg/40ct/6g
  • Sold for research purposes only

Potential Benefits of Evodiamine + Theacrine

May Help with Focus and Motivation

Theacrine has been identified as a potential enhancer of focus and motivation, offering an alternative to caffeine without the tolerance-forming effects commonly associated with its use. A 2016 study published in the Journal of Dietary Supplements reported that Theacrine supplementation led to improvements in cognitive performance, including attention and focus. [R]

By potentially promoting mental clarity and motivation, Theacrine holds promise as a natural compound for individuals seeking to enhance their cognitive performance. [R]

May Help With Weight Loss

Research suggests that Evodiamine and Theacrine hold the potential in supporting weight management efforts. Evodiamine has shown promise in reducing body weight, BMI, and fat accumulation. A notable study published in the Journal of Functional Foods in 2013 revealed that overweight test subjects who were supplemented with Evodiamine experienced significant reductions in body weight, fat mass, and waist circumference. [R]

Similarly, Theacrine has demonstrated its ability to contribute to weight loss efforts by supporting energy levels and reducing fatigue. A study published in the Journal of the International Society of Sports Nutrition in 2015 found that Theacrine supplementation led to improvements in power output and endurance during exercise. [R]

While these findings are encouraging, it is crucial to acknowledge that further research is needed to validate and better understand the weight loss effects of both Evodiamine and Theacrine. [R] [R]

May Have Anti-Inflammatory and Neuroprotective Effects

Beyond their potential contributions to weight management and cognitive performance, Evodiamine has demonstrated intriguing anti-inflammatory and neuroprotective properties. A study published in the Journal of Neuroinflammation in 2018 found that Evodiamine exhibited the ability to reduce inflammation in a mouse model of multiple sclerosis, possibly through its impact on the immune system. [R]

These anti-inflammatory and neuroprotective effects suggest that Evodiamine may have broader implications for various health conditions, necessitating further research to explore its therapeutic potential. [R]

It is important to highlight that while the current research shows promise, much of our understanding of the benefits associated with Evodiamine and Theacrine is still in its early stages. Continued investigations are essential to unravel the precise mechanisms of action and unlock the full therapeutic utility of these natural compounds. [R]

How It Works

The mechanisms of action underlying the effects of Evodiamine and Theacrine are still being actively investigated in scientific research.

Evodiamine is believed to operate through several potential mechanisms. It is thought to increase thermogenesis, which involves the generation of heat in the body, and enhance fat oxidation, the process of breaking down fats for energy. Additionally, Evodiamine may exhibit anti-inflammatory properties and have the ability to suppress appetite. A study published in the Journal of Nutritional Biochemistry in 2014 demonstrated that Evodiamine increased energy expenditure and facilitated weight loss in mice fed a high-fat diet. Activation of the TRPV1 receptor, which is involved in thermogenesis and fat metabolism, is considered a potential avenue through which Evodiamine exerts its effects.

In contrast, Theacrine is believed to share a structural similarity and a mechanism of action akin to caffeine, although with notable differences. Like caffeine, Theacrine acts as a stimulant by binding to adenosine receptors in the brain, promoting energy and focus. However, unlike caffeine, Theacrine appears to lack tolerance-forming effects. This means that it may be less likely to induce caffeine-related jitters or energy crashes that some individuals experience when consuming caffeine.

Collectively, the active constituents present in Evodiamine and Theacrine hold scientific potential for improving energy levels, enhancing focus, and possibly contributing to weight loss. Nonetheless, additional research is required to comprehensively comprehend the precise mechanisms of action and ascertain the full range of their therapeutic benefits.


When considering the combination of Evodiamine and Theacrine for research purposes, it is important to exercise caution and adhere to certain precautions. Here are some key considerations:

Consult with a qualified researcher: Before initiating any research involving the combination of Evodiamine and Theacrine, it is essential to consult with a qualified researcher or professional in the field. They can provide guidance specific to your research goals and ensure compliance with ethical and safety standards.

Use appropriate dosages: When conducting research with Evodiamine and Theacrine, it is recommended to determine and utilize appropriate dosages based on existing literature and expert advice. Starting with lower doses and gradually increasing as needed can help assess the compounds’ effects and minimize potential adverse reactions.

Adhere to safety guidelines: Ensure that all necessary safety guidelines and protocols are followed throughout the research process. This includes handling and storing the compounds appropriately, maintaining accurate records, and complying with institutional or regulatory requirements.

Remember, these precautions are intended solely for research purposes and should not be misconstrued as recommendations for human consumption. Always consult with qualified researchers or professionals who can provide guidance tailored to your specific research objectives and ensure compliance with relevant regulations and ethical considerations.

Potential Side Effects

High doses of Theacrine in research subjects may cause caffeine-like side effects such as increased heart rate, anxiety, and caffeine tolerance begins to build. Furthermore, the long-term safety of both Evodiamine and Theacrine remains relatively understudied, particularly concerning their impact on specific populations.

Given the nature of these compounds as subjects of ongoing research, it is crucial that their investigation is conducted by licensed researchers who possess the necessary expertise and resources. This ensures that the studies adhere to appropriate scientific protocols, ensuring the safety and reliability of the findings.

As research continues to unfold, it is expected that a more comprehensive understanding of the potential risks and benefits associated with Evodiamine and Theacrine will emerge. Such knowledge will be instrumental in guiding their appropriate and responsible use in various contexts.


In conclusion, the combination of Evodiamine and Theacrine holds promise for various research purposes. Evodiamine, with its potential benefits in fat burning, boosting metabolism, and suppressing appetite, may serve as an effective fat burner and aid in weight loss. Meanwhile, Theacrine offers advantages in enhancing mental focus, increasing stamina, and improving concentration, without the tolerance build typically associated with caffeine.

The active ingredients in Evodiamine and Theacrine exhibit mechanisms that contribute to their potential benefits. Evodiamine has been linked to increasing thermogenesis and energy expenditure, promoting fat loss, and potentially supporting brain health. On the other hand, Theacrine, akin to caffeine but without the associated jitters or energy crashes, stimulates the central nervous system, providing sustained energy and mental clarity.

It is important to note that the benefits of this combination are still being investigated, and further research is needed to fully understand their potential in human applications. Double-blind studies with controlled dosages and objective measures, such as increased heart rate, metabolism, and fat burning, would contribute to a more comprehensive understanding of their effects.

While Evodiamine and Theacrine show promise, it is crucial to approach their use with caution. Adhering to recommended dosages and monitoring for any potential adverse reactions is imperative.

It is also essential to recognize that Evodiamine and Theacrine are not intended as a cure or treatment for any specific disease. Their potential benefits lie in supporting various aspects of health and wellness. As with any research, the ultimate goal is to expand our knowledge and contribute to the development of potential interventions for specific conditions in the future.


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