Researchers tirelessly explore new studies to find safer alternatives to anabolic compounds and immunosuppressive drugs. In this quest, they have uncovered the potential of Melanotan 1.

Melanotan 1 (MT-1), a synthetic peptide analogue of alpha-melanocyte-stimulating hormone (α-MSH), is a subject of interest in the realm of scientific research. This peptide mirrors the natural functions of α-MSH, a hormone produced and secreted by the pituitary gland, renowned for its anti-inflammatory and fever-reducing effects.

In Europe, Melanotan 1 has found clinical applications in the prevention of phototoxicity. Phototoxicity is a condition characterized by heightened sensitivity of the skin to light, leading to skin burning, sunburn, and other sun-related damage. Furthermore, this condition has the potential to elevate the risk of developing skin cancer.

Clinical studies suggest that Melanotan 1 can increase melanin density in the skin. This quality makes the research chemical a potential candidate for skin cancer prevention. Also, it is suggested that MT-1 may induce sexual arousal although more studies are needed to confirm this.

It’s crucial to emphasize that Melanotan 1 is intended for research purposes only and is not meant for human consumption. The synthetic peptide offers a unique avenue for scientific exploration into its potential applications, particularly in addressing conditions associated with sun-related skin damage.

As research endeavors progress, Melanotan 1 continues to contribute to our understanding of the complex interplay between hormones and skin health. This product serves as a valuable tool for researchers in their pursuit of knowledge, with the ultimate goal of uncovering innovative approaches to mitigate the adverse effects of phototoxicity and related skin conditions.

Nasal sprays are preferred for studying Melanotan 1 due to their ease of use and efficient absorption. The nasal delivery method allows for controlled administration, ensuring precise dosing for research purposes. This characteristic makes nasal sprays a practical choice for investigating Melanotan 1, facilitating accurate research outcomes in a controlled and systematic manner.

Key Features

  • 98% Purity
  • Sold for research purposes only and not for human consumption
  • 100mcg per spray/10mL/10mg

Potential Benefits of Melanotan 1

1. Melanotan 1 and Skin Health

Melanotan 1, a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH), has demonstrated potential benefits in addressing erythropoietic protoporphyria (EPP), a Sun-related damage characterized by heightened sensitivity to UV rays. Findings from pivotal Phase II and III clinical trials have provided insights into the therapeutic possibilities of Melanotan 1. [R]

EPP, a painful skin condition, results from an abnormal sensitivity to sunlight, causing discomfort and limiting exposure to natural light. Melanotan 1, when explored in the context of research, has shown promise in mitigating the effects of EPP. Clinical trials have indicated that Melanotan 1 therapy, when combined with UV-B light or sunlight, was notably effective in promoting skin tanning as a response to light exposure.

It’s essential to emphasize that Melanotan 1 is intended for research purposes only and should not be construed as a product for human consumption. Researchers and scientists are investigating the potential applications of Melanotan 1, particularly in conditions such as EPP, where the sensitivity to sunlight poses significant challenges.

2. Melanotan 1 and Inflammation

Melanotan 1, a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH), has been the subject of studies exploring its potential anti-inflammatory properties and their potential impact on various diseases.

Research findings suggest that Melanotan 1 induces antioxidant activities, contributes to DNA repair, and modulates the inflammatory process. These properties may hold significance in understanding its potential applications in mitigating inflammatory responses within the body.

In specific studies using a mouse model of skin inflammation, Melanotan 1 demonstrated inhibitory effects on the production of inflammatory substances, including TNF-α and IL-6. These findings indicate a potential role for Melanotan 1 in regulating the inflammatory pathways associated with skin conditions, providing valuable insights into its broader impact on inflammatory processes. [R]

It’s essential to highlight that Melanotan 1 is intended for research purposes only and is not intended for human consumption. Researchers are exploring the peptide’s properties to deepen our understanding of its effects on inflammation and potential therapeutic applications.

3. Melanotan 1 and Heart Health

In studies involving mice with atherosclerosis, a condition characterized by plaque formation within the heart arteries, Melanotan 1 demonstrated a preventive effect on plaque formation and heart dysfunction. These observations provide insights into the potential role of Melanotan 1 in mitigating the development of atherosclerotic plaques, which are linked to cardiovascular issues. [R]

Additionally, a separate mouse study revealed that Melanotan 1 induced relaxation of the heart arteries. This relaxation contributed to an improvement in blood circulation, emphasizing a potential mechanism through which Melanotan 1 may positively influence cardiovascular health. [R]

Based on the mentioned studies, Melanotan 1 could be an ideal candidate for further drug development since it may control high blood pressure.

It’s essential to underscore that Melanotan 1 is intended for research purposes only and is not intended for human consumption. Melanotan is not an approved drug for heart attack although it has the potential to promote good heart health. The focus of these studies is to explore the peptide’s effects on specific physiological mechanisms, shedding light on its potential applications in heart protection.

4. Melanotan 1 and Blood Pressure

Melanotan 1 has exhibited potential benefits in protecting against elevated blood pressure, as observed in studies involving hypertensive mice.

The research findings indicate that Melanotan 1 demonstrated protective effects specifically in hypertensive mice, without influencing those with normal blood pressure. This specificity highlights a potential role for Melanotan 1 in modulating blood pressure levels under hypertensive conditions. [R]

It is crucial to emphasize that Melanotan 1 is intended for research purposes only and is not intended for human consumption. The focus of these studies is to explore the peptide’s effects on specific physiological mechanisms, offering insights into its potential applications in addressing elevated blood pressure.

5. Melanotan 1 and Stroke

Melanotan 1, a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH), has exhibited potential benefits in animal models, particularly in the context of stroke recovery.

In studies involving gerbil models of stroke, the administration of Melanotan 1 and its counterpart, Melanotan 2, after a stroke event demonstrated positive outcomes. The observed effects included a reduction in brain damage and an improvement in the recovery of learning and memory functions. [R]

It’s important to note that Melanotan 1 is intended for research purposes only and is not suitable for human consumption.

6. Melanotan 1 and Fat Loss

Evidence from studies suggests that Melanotan 1, a synthetic peptide analog of alpha-melanocyte-stimulating hormone (α-MSH), may possess potential fat-burning properties, as observed in experiments involving mice. [R]

In these studies, Melanotan 1 demonstrated the ability to stimulate fat burning, a process attributed to the activation of the melanocortin-5 receptor (MC5R). This particular receptor plays a role in regulating energy balance and metabolism.

7. Melanotan 1 and Cognitive Function

In mouse models simulating Alzheimer’s disease (AD), the administration of a minimal dose of Melanotan 1 demonstrated positive effects in mitigating cognitive decline. The observed outcomes point towards a potential avenue for further exploration in addressing cognitive impairments associated with neurodegenerative conditions.

In separate studies involving mice, the daily administration of nanomolar doses of Melanotan 1 over a 50-day period revealed noteworthy results. This included a significant reduction in AD-related biomarkers and cognitive recovery, attributed to the stimulation of the melanocortin-4 receptor (MC4R), which, in turn, facilitated neurogenesis, or the formation of nerve cells. [R]

How Does Melanotan-1 Work?

Melanotan 1 operates primarily by elevating the process of melanogenesis, the production of melanin, a pigment responsible for skin coloration. This synthetic peptide has the potential to stimulate melanin production.

The peptide does this by binding to the melanocortin 1 receptor (MC1R), a crucial component in the melanin production pathway. Through this interaction, Melanotan 1 induces an increase in melanin synthesis and melanocyte proliferation, leading to skin darkening.

The structural composition of Melanotan 1, a 13-amino acid linear peptide, distinguishes it from its natural counterpart, α-MSH. Notable differences include the substitution of norleucine for the fourth amino acid and D-phenylalanine for the seventh amino acid. These alterations contribute to its increased potency and resistance to degradation compared to α-MSH.

In research settings, Melanotan 1 has demonstrated a heightened affinity for the MC1R receptor, enhancing its effectiveness in promoting tanning while minimizing the risk of sunburn. The peptide’s capacity to reduce sun damage is particularly relevant for skin exposed to ultraviolet rays.


When researching the use of Melanotan 1 nasal spray, it is essential to take certain precautions. Here are some precautions to keep in mind:

Observe best practices for studying research chemicals

Studying research chemicals requires a responsible and informed approach to ensure safety and meaningful scientific exploration. Research chemicals, also known as designer drugs or experimental compounds, are substances synthesized for scientific investigation or exploration of their properties.

Follow the recommended dosage in the warning section

Adhere to the recommended dosage instructions outlined on the product label. Avoid a significant increase of the suggested dose to minimize the risk of potential adverse effects among test subjects.

Potential Side Effects of Melanotan 1 Nasal Spray

Side effects of Melanotan 1 are generally rare, and test subjects may experience the following:

  • Facial flushing
  • Gastrointestinal upset
  • Increased moles and freckles
  • Loss of appetite
  • Nausea
  • Tiredness
  • Unwanted tanning
  • Vomiting

It’s important to note that while these side effects are reported, their occurrence is infrequent. As with any research substance, the focus should remain on systematic investigation and understanding potential effects, rather than endorsing or encouraging use for human consumption.


In conclusion, the availability of Melanotan 1 Nasal Spray for sale raises intriguing possibilities for researchers exploring the peptide’s diverse applications. Melanotan 1, a synthetic analog of alpha-melanocyte-stimulating hormone, has been investigated for its potential benefits, ranging from sunless tanning to protective effects against UV radiation, and may even improve cognition in animal studies.

It’s crucial to approach the availability of Melanotan 1 Nasal Spray with a research-oriented mindset, steering clear of promotional undertones and strictly adhering to the understanding that this product is intended for research purposes only. The diverse range of potential benefits, such as its impact on skin conditions, protection against phototoxicity, and potential cognitive benefits, underscores the importance of ongoing scientific exploration.