MK-677 Ibutamoren

A research substance called MK 677 Ibutamoren has received a lot of attention recently due to its potential health advantages. It is frequently referred to as a “growth hormone secretagogue” because it may have the potential in triggering the body’s release of growth hormone levels.

But what exactly is MK 677 Ibutamoren, and is it safe to use it? The details listed below provide an overview of MK 677 Ibutamoren.

It’s important to keep in mind that MK 677 Ibutamoren, along with other research compounds, is intended only for research purposes and not for human consumption. offers this product only for sale for research use and does not endorse or recommend it for any other purpose. If you are using this product for research, be sure to follow all handling instructions and safety precautions.

What is MK 677 Ibutamoren?

Growth hormone plays an important role in muscle growth and repair and MK 677 Ibutamoren is a research chemical that’s designed to help a body produce more growth hormone secretagogue. (R)

Growth hormone is really important for building muscle mass and maintaining strong bones, That is why it has drawn a lot of attention when it comes to other potential benefits of increasing growth hormone levels and GH secretion, like improved sleep quality and a reduced risk of certain age-related diseases. (R) (R)

Below is the chemical composition of MK 677 Ibutamoren: (R)

Product Name:  MK-677 Ibutamoren 
Application: Scientific
CAS: 159634-47-6
Molar Mass: 528.67 g·mol−1
Chemical Formula: C27H36N4O5S
IUPAC Name: 2-amino-2-methyl-N-[1-(1-methylsulfonylspiro[2H-indole-3,4′-piperidine]-1′-yl)-1-oxo-3-phenylmethoxypropan-2-yl]propanamide
Synonyms: MK-677; MK-0677; L-163,191; Oratrope
Storage: Minimize open-air exposure, store in a cool dry place
Variants: MK 677 Ibutamoren Powder (1000mg) and Liquid (30ml/ 33mg per ml/ 1000mg) (30ml/ 67mg per ml/ 2000mg)

How Does MK 677 Ibutamoren Work?

MK 677 works by stimulating the growth hormone release in the body. Your pituitary gland naturally produces growth hormone, which is required for controlling a variety of bodily processes such as bone development, muscle mass, and fat-free mass. (R)

Unlike growth hormone and other growth hormone secretagogues, MK 677 Ibutamoren, stimulates the secretion of more growth hormones in the body. It promotes the secretion of the growth hormone (GH) and increases insulin-like growth factor 1 (IGF-1). Ibutamoren increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors which instructs your pituitary gland in growth hormone release. It has been demonstrated to increase the GH release and produces sustained increases in plasma levels of several hormones including growth hormone and IGF-1, but without affecting cortisol levels. It has the potential to promote muscle development and repair, increase bone density, and accelerate fat-free mass by increasing the body’s growth hormone levels and maintaining good health. (R) (R)

What are the Potential Applications of MK 677 Ibutamoren?

The Gain in Muscle Strength and Lean Body Mass

MK 677 was shown in a clinical trial to increase lean body mass and improve muscle strength in older adults with hip fractures. It works by potentially increasing the production of growth hormones, which can increase muscle mass and strength. In a study of elderly adults as test subjects with hip fractures, those given MK 677 Ibutamoren had greater lean body mass and muscle strength than those given a placebo. (R)

Increasing Bone Density

A potential study discovered that Ibutamoren MK 677 increases bone mineral density, in postmenopausal women with osteoporosis. It functions by boosting the production of IGF-1, a protein crucial for the development and growth of bones. When compared to a placebo group, postmenopausal women with osteoporosis who took MK 677 Ibutamoren had higher bone mineral density. In another study conducted, MK-677 increases markers of bone turnover in healthy and functionally impaired elderly patients. (R) (R)

Adipose Tissue Mass Reduction

In a clinical trial, Ibutamoren MK 677 was found to decrease the mass of adipose tissue in adults with obesity. To achieve fat-free mass, MK 677 Ibutamoren works by boosting the production of potential growth hormones. In a study involving obese subjects, those who took MK 677 Ibutamoren experienced less adipose tissue mass than those who received a placebo. (R)

Enhanced Sleep Efficiency

In one study on normal young men, MK 677 was found to enhance sleep quality and boost the quantity of rapid eye movement (REM) sleep. Growth hormone and GH release are crucial for controlling sleep and are produced more frequently as a result of MK 677 Ibutamoren’s action. In comparison to a control group, the test subjects who took MK 677 Ibutamoren reported better sleep quality and more REM sleep. (R)

Treatment for Growth Hormone Deficiency

Ibutamoren MK 677 has been investigated as a possible treatment for growth hormone deficiency in both children and adults because of its potential to increase levels of both growth hormone and insulin-like growth factor 1 (IGF-1) in the body. Growth hormone is produced as a result of MK 677 Ibutamoren’s stimulation of this process which is required for normal growth and development. In a clinical trial for growth hormone deficiency, the test subjects were children who received MK 677 Ibutamoren and grew taller than those who received a placebo. (R)

Safety and Side Effects

  • Increased Appetite: MK 677 Ibutamoren has been shown to increase appetite, which can lead to body weight gain. (R)
  • Water Retention: MK 677 Ibutamoren has been shown to cause water retention, which can lead to bloating and swelling. (R)
  • Fatigue: MK 677 Ibutamoren has been shown to cause fatigue that may be related to the chemical effects on the body’s growth hormone levels and metabolism. (R)
  • Increased Risk of Diabetes: MK 677 Ibutamoren has been shown to increase insulin resistance, which can lead to an increased risk of diabetes. (R)
  • Potential Interactions with Medications: The most frequent side effects of MK 677 Ibutamoren may interact with certain medications, such as insulin and diabetes medications. (R)
  • Unknown Long-term Effects: Since MK 677 Ibutamoren is a relatively new research chemical, there is limited information on its long-term effects on body composition. (R)

Take note that MK 677 Ibutamoren has not been approved by regulatory agencies such as the FDA (Food and Drug Administration) for any medical use. It is still considered a research chemical and is not legal for human consumption in many countries. (R)


As MK 677 Ibutamoren is a relatively new research chemical, there is still much to be explored in terms of its potential future research that will likely continue to explore its potential benefits and risks for a range of conditions and better understand how it affects the body composition. Some potential areas of laboratory research use include long-term anabolic effects, specific conditions, and mechanisms of action. (R)


What is MK 677?

MK 677, also known as Ibutamoren, is a non-peptide growth hormone gh secretagogue that is often in laboratory research use and bodybuilding communities to sustained increase muscle mass, promote fat-free mass, and improve overall athletic performance.

How does MK 677 work?

MK 677 works by stimulating the release of growth hormone and insulin-like growth factor 1 (IGF-1) in the body. This can help to increase muscle mass, reduce body fat, and improve bone density.

Is MK 677 legal?

MK 677 powder is not approved for human consumption or use by the FDA. However, it is legal to purchase and use for research purposes.

What are the potential benefits of MK 677 in research?

MK 677 has been shown to increase muscle mass, improve bone density, and promote fat loss in research studies. It may also have cognitive benefits such as improving memory and reducing anxiety.

Can MK 677 be stacked with other compounds in research?

Yes, MK 677 powder can be stacked with other compounds in research to potentially enhance its effects. Commonly stacked compounds include SARMs and testosterone.

Where to Buy MK 677 Ibutamoren?

When it comes to Nootropics and other research compounds is among the most reliable and novel companies available. We offer targeted solutions with lab-tested purity for your specific needs.


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