N-Acetyl L-Cysteine (NAC)


N-acetyl L-cysteine, or NAC, is a sulfur-containing amino acid and a stable form of acetylcysteine. This powerful antioxidant has gained significant attention for its alleged health benefits and research potential.

NAC is well known for its alleged ability to support a balanced immune system function and promote liver health by increasing glutathione levels, the body’s master antioxidant. However, the benefits of NAC extend far beyond these two areas, as it has also been shown to have massive potential to support healthy brain and neuronal tissues.

N Acetyl L Cysteine Product Details

In 1963, NAC was initially sanctioned by the FDA as a medication for respiratory issues. [R]

It is also employed to avert severe liver impairment due to acetaminophen overdose. Today, it is being investigated for other alleged health advantages.

NAC N-Acetyl-Cysteine is a stable form of amino acid l cysteine and is being studied for its potential as a vitamin boost that can provide a range of health benefits. Below is the chemical’s useful description, n acetyl cysteine product details:

  • CAS Number: 616-91-1
  • Molar Mass: 163.20 g/mol
  • Chemical Formula: C5H9NO3S
  • IUPAC Name: N-acetyl-L-cysteine
  • Synonyms: N-Acetylcysteine, N-Acetyl-L-cysteine, NAC, Acetylcysteine, N-Acetyl-3-(mercapto-2-methylpropionyl)aminopropionic acid, Acemuc, Mucomyst, Acetadote

Key Features

  • 98% Purity
  • 50g | 100g
  • FDA-approved for respiratory illness

Potential Benefits of N-Acetyl L-Cysteine NAC

Scientists have explored the potential benefits of using N-acetyl cysteine (NAC) as a dietary supplement to address various health concerns. Some studies suggest that NAC may be helpful in the following ways:

FDA Approval for Acetaminophen Poisoning

N-Acetyl Cysteine (NAC) has been FDA-approved as a potential treatment for acetaminophen toxicity, which can cause liver damage when taken in high doses. Research suggests that NAC detox regulators could increase glutathione levels, a known liver detoxifier, which aids in deactivating the hazardous byproduct of acetaminophen known as N-acetyl-p-benzoquinone imine (NAPQI). [R]

However, it should be noted that NAC cannot reverse any damage already caused by the drug. To be most effective, researchers are hypothesizing that NAC should be administered within eight hours after taking acetaminophen. [R]

N-Acetyl L-Cysteine May Reduce Symptoms of Respiratory Disease

N-Acetyl L-Cysteine (NAC) has shown potential as a treatment for certain respiratory tract disorders, including chronic bronchitis and chronic obstructive pulmonary disease (COPD). These conditions are characterized by inflammation and excessive mucus production in the airways, which can lead to impaired breathing and weakened lungs. [R]

NAC works by potentially breaking up and thinning mucus secretions in the airways, making it easier to cough out and clear the airway. This can potentially improve respiratory health and alleviate symptoms. However, further research is needed to fully understand the effectiveness and safety of NAC in treating respiratory diseases. [R]

N-Acetyl L-Cysteine May Benefit Mental Health Conditions

Emerging research suggests that NAC may be a promising treatment option for certain mental health issues. [R]


A small 2018 study discovered that when used in combination with antipsychotic medication, NAC potentially reduced symptoms of schizophrenia. The compound was associated with improvements in negative symptoms such as emotional expressiveness, thought and speech productivity, motivation, and attention span. [R]


An analysis of data from multiple trials, including information from 574 depression patients and healthy volunteers, found that NAC has the potential to improve depressive symptoms and daily functioning within three to six months of administration. [R]

Furthermore, by reducing oxidative stress in the brain, NAC may regulate mood. A research of 76 depressed test subjects found that NAC had increased antioxidant levels in their brains. [R]

Bipolar Disorder

NAC is currently being researched for its potential to treat bipolar disorder patients’ chronic health issues, such as heart disease and hormone imbalances. [R]

An exploratory, small-scale investigation discovered that NAC had an indirect impact on overall health, antioxidant status, and inflammation in 51% of bipolar patients with cardiovascular or hormonal problems. [R]

Although the available scientific data comes from small-scale studies, larger clinical studies are underway to investigate the potential benefits of NAC for bipolar disorder. Purerawz sells NAC for research purposes only. [R]

Obsessive-Compulsive Disorder (OCD)

By regulating glutamate and raising antioxidant levels in the brain, NAC may potentially help with OCD treatment. A study of 44 OCD patients found that adding NAC to standard medication alleviated symptoms, even in those with severe cases. [R]

In a study of 48 OCD patients who had not responded to traditional pharmacological treatments, NAC was found to alleviate symptoms after three months of supplementation without significant negative side effects. [R]

Overall, a comprehensive evaluation suggests that NAC may have a promising future for treating obsessive-compulsive disorders with relatively few adverse effects. [R]

Supports Healthy Brain Function

NAC has shown promise in enhancing brain function and reducing symptoms of neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease, as well as lessening neuropathic pain caused by central nervous system injuries. While more research is needed to confirm these effects, NAC’s ability to raise glutathione levels and prevent oxidative stress may play a role in its potential neuroprotective effects. [R]

Potential Efficacy Against Viral Infections

Clinical studies are ongoing to determine the potential efficacy of NAC against SARS-CoV-2. However, research suggests that NAC can potentially reduce the severity, duration, and frequency of influenza, common colds, recurrent bronchitis, and pneumonia. NAC may prevent the replication of viruses, strengthen the immune system, and fight viral illnesses, making it a potentially useful supplement for those with viral infections. [R]

Improves Male Fertility

NAC has been found to potentially improve sperm quality and lower oxidative stress in infertile men. In a small 2019 study, subjects who took NAC for three months had significantly higher sperm counts and motility, as well as reduced sperm DNA damage and abnormal structure. These findings suggest that NAC may increase overall sperm quality and improve male infertility. [R]

While NAC has shown promise in improving these health conditions, further research is needed to confirm its efficacy and safety. If you’re researching NAC, it’s important to follow safety protocols to avoid any unwanted incidents. [R]

How It Works

N-Acetyl L-Cysteine, or NAC, is an amino acid that is formed when L-cysteine is modified by the addition of an acetyl group. N Acetyl Cysteine is a powerful antioxidant that can scavenge free radicals and reduce oxidative stress in the body, which can contribute to cellular damage and aging. One of the primary mechanisms of action of NAC is its ability to increase the production of glutathione, a key antioxidant that is critical for maintaining cellular health and protecting against oxidative damage.

In addition to its potential antioxidant properties, N Acetyl Cysteine has been found to have a number of other potential beneficial effects on the body. For example, NAC may promote blood thinning and improve circulation, which can be useful for individuals with cardiovascular disease or other circulatory disorders. NAC has also been shown to have potential anti-inflammatory effects, and it may help to modulate the immune system by regulating the production of cytokines and other immune signaling molecules.

Another potential benefit of NAC is its ability to interact with protein structures in the body, which can help to promote healthy cellular function and structure. Some studies have even suggested that NAC may have life-extending properties, although more research is needed to confirm this effect.


While N-Acetyl L-Cysteine, or NAC, can be beneficial, there are certain research groups that should avoid studying its effects. NAC should not be studied on subjects who are taking blood thinners, as it may increase the risk of bleeding. It is also important to choose a soy-free NAC product if test subjects have a soy allergy or sensitivity.

Potential Side Effects

Possible side effects of NAC include diarrhea, constipation, nausea, stomach upset, and vomiting. 


N-Acetyl L-Cysteine (NAC) is a potential future dietary supplement that has been evaluated for various potential health benefits. NAC may serve as a detox regulator and provide radical protection to support cellular health. NAC is gluten-free, non-GMO, and may promote healthy brain function by supporting neuronal tissues.

It is also believed that NAC may aid in the prevention of oxidative stress that can damage cells. Additionally, NAC could improve symptoms of respiratory diseases, mental health issues, and male infertility. However, larger clinical studies are needed to confirm these effects. 


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