Nowadays, maintaining mental acuity and concentration is increasingly crucial. Numerous people are looking for ways to improve their cognitive abilities and overall brain function. This is where N-Acetyl Selank gets the scene. This modified version of the well-known peptide Selank may improve cognitive performance and unlock your full mental potential.

N-acetyl Selank is classified as a nootropic, a term used to describe substances that are believed to enhance cognitive functions such as memory, creativity, focus, and motivation. These cognitive enhancers, also known as smart drugs, have gained significant attention in recent years due to their potential to provide a mental edge in our demanding lives.[R]

Derived from Selank, N-Acetyl Selank takes the original peptide’s benefits and enhances them through a simple modification. By adding an acetyl group to the amino acid sequence, [R] N-Acetyl Selank offers improved stability and better penetration of the blood-brain barrier. This means that it has a greater chance of reaching its target in the brain, where its effects are believed to be most pronounced. [R]

In the following sections, we will look deeper into the potential benefits of N-Acetyl Selank, explore the scientific research supporting its use. So, if you’re ready to uncover the secrets of cognitive enhancement and explore the potential of N-Acetyl Selank, read on.

Key Features

RCD.Bio offers N-Acetyl Selank with the following specifications:

  • A purity of 98%, verified by third-party laboratory testing.
  • Available in 30mg powder form

N-Acetyl Selank

  • CAS Number: 129954-34-3
  • Molar Mass: 751.887 g·mol−1
  • Chemical Formula: C33H57N11O9
  • IUPAC Name: 1-[2-({1-[2-({1-[6-Amino-2-(2-amino-3-hydroxy-butyrylamino)-hexanoyl]-pyrrolidine-2-carbonyl}-amino)-5-guanidino-pentanoyl]-pyrrolidine-2-carbonyl}-amino)-acetyl]-pyrrolidine-2-carboxylic acid
  • Synonyms: Selanc; L-threonyl-L-lysyl-L-prolyl-L-arginyl-L-prolylglycyl-L-Proline

How Does N-Acetyl Selank Work?

N-Acetyl Selank, a peptide with potential therapeutic benefits, is believed to work through various mechanisms. Although the exact workings of this synthetic peptide are not fully understood due to limited research, several proposed mechanisms shed light on its potential benefits.

One proposed mechanism suggests that N-Acetyl Selank may interact with GABA receptors, which are involved in anxiety regulation. Some studies indicate that it may act as a ligand for GABA receptors, similar to benzodiazepines, a class of anti-anxiety medications. This potential interaction could explain the possible anti-anxiety effects attributed to N-Acetyl Selank.[R][R][R]

Another beneficial effect of N-Acetyl Selank is its potential to increase brain-derived neurotrophic factor (BDNF) levels. BDNF is a crucial molecule necessary for memory and learning. Research has shown that selank administration intravenously can result in elevated BDNF levels in the rat brain. This increase in BDNF levels may contribute to the purported cognitive effects associated with N-Acetyl Selank.[R][R]

Furthermore, N-Acetyl Selank is thought to influence neurotransmitter levels. Studies have shown that it can impact the levels of serotonin, dopamine, and norepinephrine, which are essential for mood regulation and cognitive function. While the exact mechanism of action is not fully understood, N-Acetyl Selank has been observed to decrease serotonin and dopamine levels in some cases while increasing norepinephrine levels. However, more research is needed to fully comprehend how N-Acetyl Selank influences neurotransmitter levels.[R]

Lastly, N-Acetyl Selank may help maintain stable levels of enkephalins, natural peptides with potent analgesic effects. Research suggests that N-Acetyl Selank inhibits the enzymes responsible for degrading enkephalins, thus promoting their stability. This stabilization of enkephalin levels could potentially contribute to the pain perception giving relieving properties associated with N-Acetyl Selank.[R]

While these mechanisms offer potential benefits, it is important to note that further research is necessary to fully understand and validate the effects of N-Acetyl Selank. This article emphasizes that it does not promote the use of N-Acetyl Selank for human consumption and serves solely as an informative piece on its potential mechanisms of action.

The scientific basis behind the benefits of N-Acetyl Selank

Research on N-Acetyl Selank (NA-Selank) is still relatively limited compared to its parent peptide Selank.

Anxiety and Stress

Anxiety and stress are common issues that many face in their daily lives. The potential benefits of Selank in managing anxiety and stress have been explored in various studies, providing valuable insights into its effects on these conditions.

Selank has been found to have a special effect in reducing anxiety, known as an anxiolytic effect. It is interesting to note that Selank can also influence the effects of traditional anxiety medications called benzodiazepines. In a study on rats experiencing unpredictable chronic mild stress, a combination of Selank and diazepam (a benzodiazepine) was especially effective in possibly reducing anxiety. This indicates the potential of Selank as an adjunct therapy for anxiety management.[R]

In another study, Selank was investigated as an immunomodulatory peptide for test subjects with anxiety-asthenic disorders. The findings suggest that Selank may have the ability to regulate cytokine balance and influence gene expression, particularly targeting IL-6. This indicates its potential therapeutic value in modulating the immune system. Additionally, the adaptogenic properties of Selank make it an attractive option for old test subjects and those exposed to environmental stressors, as it may enhance immune response and reduce the risk of infectious diseases. However, further research and clinical trials are needed to validate these findings and explore the full potential of Selank as an immunomodulator in different populations.[R]

It is important to note that while these studies provide valuable insights, further research and clinical trials are necessary to fully understand the effectiveness and safety of Selank in managing anxiety and stress. This article serves as an informative overview of the potential benefits of Selank and does not promote its use without proper medical guidance from qualified professionals.


Selank, a peptide that has been studied in animal experiments, shows the potential to assist with the control of the coagulation process, which involves blood clotting. It has demonstrated some anti-coagulant properties, suggesting its potential usefulness in this area. [R] Studies conducted on rat mesenteric arteries have further supported these observations, indicating that Selank may be beneficial in hypercoagulable conditions. These findings highlight the potential of Selank as a compound with anti-coagulant properties, although further research is needed to fully understand its effects and validate its potential therapeutic applications in this context. [R]

Learning and Memory

Selank, when administered intranasally to rats at a dosage of 200 microg/kg, has been found to alter the transcriptional profile of the rat hippocampus. The study revealed that Selank treatment can influence ion homeostasis in the cells of the hippocampus by affecting the mRNA levels of genes encoding proteins associated with the plasma membrane. This suggests that Selank may have the ability to modulate ion-dependent processes, which in turn could impact the regulation of learning and memory. These findings highlight the potential of Selank in influencing cognitive functions through its effects on the hippocampus.[R]

It is important to note that these studies were conducted on animals, and further research is needed to determine the precise mechanisms through which Selank affects learning and memory in humans.

Alcohol Withdrawal

In a study examining the effects of Selank on alcohol withdrawal symptoms, rats were administered Selank after being given a 10% ethanol solution as their sole source of drinking for six months. At the conclusion of the trial, tests were conducted to assess the impact of Selank. The results revealed that Selank completely eliminated the anxiety induced by ethanol withdrawal. This suggests that Selank has the potential to alleviate the anxiety symptoms associated with alcohol withdrawal.[R]

Moreover, Selank was found to not only alleviate anxiety but also alcohol withdrawal-induced mechanical allodynia. Mechanical allodynia is a condition that causes pain in response to harmless stimuli, such as light touch. Untreated, it could contribute to a relapse. However, Selank demonstrated promise in reducing both anxiety and mechanical allodynia associated with alcohol withdrawal, indicating its potential as a treatment for withdrawal symptoms. [R]

Further studies involving human subjects are necessary to validate these findings and determine the possible potential of Selank as a treatment for alcohol withdrawal symptoms.


In a mouse study aimed at examining the effects of Selank on depression symptoms, it was found that high doses of Selank may suppress depressive behaviors in rats. This suggests that Selank has the potential to exhibit antidepressant properties and may be effective in alleviating symptoms associated with depression.[R]

Selank’s ability to suppress depressive behaviors in rats paves the way for future research into its mechanism of action and potential therapeutic applications in the treatment of depression. Nevertheless, it is essential to approach these findings with caution and to await extensive research to substantiate the effects of Selank on depression symptoms.

Sleep Enhancement

Research suggests that Selank may have a positive impact on sleep patterns, particularly in individuals with general anxiety disorders. It is believed that Selank may have a normalizing effect on the equilibrium of sleep patterns, helping to regulate the balance between sleep and alertness. [R]

The potential of Selank in enhancing sleep represents an intriguing area of study, and future research endeavors will help to shed more light on its specific effects and applications in the realm of sleep enhancement.

Immunomodulatory Effects

In studies conducted on mice with acute immunological stress, it has been observed that Selank exhibits immunomodulatory effects. The results indicate that Selank therapy has the potential to enhance certain indicators of the immune system, such as T-cell proliferation and cytokine production. Additionally, it was found that Selank can modify the activity of natural killer (NK) cells, suggesting its ability to influence immune responses.[R]

The immunomodulatory effects of Selank are of huge interest and hold potential for further therapeutic applications. Continued research will help us understand the mechanisms underlying Selank’s immunomodulatory properties and its potential benefits for improving immune function.


In an animal trial involving rats fed a high-fat diet, the administration of Selank resulted in a significant decrease in total cholesterol levels by 58%. Additionally, triglyceride levels were reduced by 22% alongside the decline in cholesterol levels. These findings suggest that Selank treatment may have the potential to positively influence lipid profiles and metabolic parameters related to cholesterol and triglyceride levels. [R]

Furthermore, the study revealed that rats fed high-fat meals did not experience significant weight gain during the Selank treatment. The average weight gain was only 6 grams, indicating that Selank may affect the accumulation of fat mass in rats consuming a high-fat diet. These results imply that Selank therapy may have an impact on the way fat mass is accumulated in the body, potentially contributing to the regulation of body weight and metabolism.[R]

The results of this animal trial suggest that Selank holds promise as a compound that can positively influence lipid profiles and potentially regulate weight gain in the context of a high-fat diet. However, further research is necessary to determine the effects of Selank on cholesterol and weight management in humans.


N-Acetyl Selank, like other similar peptides, is typically used for research purposes and is not approved for human consumption by regulatory authorities such as the FDA.

The information presented here is for educational purposes only and should not be construed as medical advice. N-Acetyl Selank is intended for laboratory research use only as a research chemical and is not intended for human consumption.

Potential side effects

It is well known that selank and similar peptides have relaxing and anxiolytic properties thus can cause mild exhaustion or drowsiness. Selank study has so far revealed minimal unfavorable outcomes. To fully comprehend the advantages of selank peptide and its adverse effects on humans, more clinical research is necessary. [R]

Where Can I Buy N-Acetyl Selank Online? offers N-Acetyl Selank for laboratory research use only.

When buying N-Acetyl Selank, it is important to choose a reputable seller who provides quality products. At, each product is accompanied by a third-party-issued Certificate of Analysis showing the identification, purity, and concentration of our product. Some also offer N-Acetyl Selank amidate and offer this cosmetic peptide.


N-Acetyl Selank is a modified form of the peptide Selank, which is renowned for its cognitive-enhancing properties. It is categorized as a nootropic and has attracted attention for its ability to enhance mental acuity and focus. N-Acetyl Selank may enhance the stability and permeability of the blood-brain barrier, thereby potentially enhancing its brain effects. N-Acetyl Selank is believed to interact with GABA receptors, increase brain-derived neurotrophic factor levels, influence neurotransmitter levels, and maintain stable enkephalin levels, though the exact mechanisms of action are not fully understood. These mechanisms suggest potential benefits for generalized anxiety disorder, stress, alcohol withdrawal, depression, sleep patterns, and immune function management. However, additional research is required to fully comprehend and validate N-Acetyl Selank’s effects. Importantly, N-Acetyl Selank is not approved for human consumption and should only be used for research purposes in the laboratory. Bodily introduction into is strictly forbidden.


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PLEASE NOTE: All products offered by are intended for laboratory and research purposes only. They are not intended for use on animals or humans.