Nicotinamide riboside chloride commonly abbreviated as NRC, a type of vitamin B3 often known as niacin or nicotinamide, is the source of the chemical nicotinamide riboside chloride (NRC). NRC is primarily produced through chemical synthesis for use in nutritional supplements and scientific research, while NR is naturally available in a variety of food sources, including milk and several vegetables. This substance has drawn interest for its possible health advantages, primarily because of its function in increasing the body’s levels of nicotinamide adenine dinucleotide (NAD+). NAD+ is an essential coenzyme involved in a variety of cellular functions, including potential enhanced oxidative metabolism, DNA repair, and enzyme control. [R]
The term “chloride” in Nicotinamide Riboside Chloride indicates that chloride ions are bound to this particular form of NR. The addition of chloride ions improves the bioavailability and stability of NR, making it simpler to manufacture and use as a dietary supplement. The chloride salt form of NR is typically more stable and simpler to handle. The form “pyridine nucleoside” refers to the pyridine ring present in the chemical structure of Nicotinamide Riboside. Nucleosides are composed of a sugar (in this case, ribose) and a nitrogenous base (in this case, the pyridine ring).
Key Features of Nicotinamide Riboside Chloride
RCD.Bio offers Baicalin with the following specifications:
- A purity of 98%, verified by third-party laboratory testing.
- Available in capsule form
Nicotinamide Riboside Chloride [R]
- CAS Number: 23111-00-4
- Molecular weight: l 290.70 g/mol
- Chemical Formula: C11H15ClN2O5
- Synonyms: Nicotinamide ribose chloride, Niagen
- IUPAC Name: 1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]pyridin-1-ium-3-carboxamide;chloride
How It Works
NAD+, a crucial coenzyme involved in several cellular processes, is produced by Nicotinamide Riboside Chloride (NRC), which functions by acting as a precursor to NAD+. When you eat NRC, your body converts it into nicotinamide riboside (NR). After that, NR is transformed into nicotinamide mononucleotide (NMN), another substance necessary for the production of NAD+.
NAD+ is essential for the creation of cellular energy, especially in the mitochondria, where it makes it easier for nutrients to be converted into energy. NAD+ also functions as a cofactor for enzymes involved in metabolic processes and DNA repair. The purpose of NRC supplementation is to raise NAD+ levels in order to improve the effectiveness of various cellular functions. Potentially can improved energy metabolism, more efficient DNA repair mechanisms, and other cellular processes related to health and longevity have all been connected to this potential increase in NAD+ levels. It’s crucial to stress that even while NRC has potential, further study is necessary to properly comprehend its mechanics and long-term impacts. [R]
Nicotinamide Riboside Chloride (NRC) Research
Numerous studies have been conducted on the potential application of Nicotinamide Riboside Chloride (NRC) capsules. Below are some of the relevant findings on the vitamin products:
NRC in Energy Metabolism
By raising the body’s levels of NAD+, which promote many aspects of healthy aging, nicotinamide riboside chloride (NRC) may have positive effects on energy metabolism. Each of your cells has the helper molecule NAD+, which can be used to activate specific sirtuins and other enzymes that may aid in healthy aging. According to studies, sirtuins may restore DNA damage, increase stress resistance, lessen inflammation, and provide other advantages that support healthy aging. A recent study that was included in a novel food application evaluated the metabolic benefits of NRC supplementation and discovered that it enhanced insulin sensitivity and glucose metabolism in healthy overweight people. The body receives NAD+ from NRC, which is a precursor to NAD+ but further studies are needed to test its effectivity in human body. [R] [R]
NRC on DNA Repair:
By raising the body’s levels of NAD+, which promote many aspects of healthy aging, nicotinamide riboside chloride (NRC) may have advantages for DNA repair. Each of the cells has the helper molecule NAD+, which can be used to activate specific sirtuins and other enzymes that may aid in healthy aging. According to studies, sirtuins may restore DNA damage, increase stress resistance, lessen inflammation, and provide other advantages that support healthy aging. It has been demonstrated that nicotinamide (NAM), a precursor to NAD+, improves DNA repair by promoting unscheduled DNA synthesis (UDS) and raising DNA repair. The presence of functional repair mechanisms is necessary for nicotinamide to improve DNA repair. [R] [R] [R]
NRC on Metabolic Health
Increased levels of NAD+, which support many aspects of healthy aging, have been linked to possible advantages for metabolic health using nicotinamide riboside chloride (NRC). The metabolic benefits of NRC supplementation were examined in a recent study that was included in a novel food application. It was discovered that it potentially enhanced insulin sensitivity and glucose metabolism in healthy overweight people. NRC has been evaluated by the European Food Safety Authority (EFSA) for its safety and effectiveness in meal replacement products and nutritional drink mixes, and it has been given the go-ahead to be used at doses up to 300 mg daily for the general populace. [R] [R]
NRC on Immune function
As it is a component of a professional-grade formulation to promote immune function, nicotinamide riboside chloride (NRC) may provide advantages for immune system performance. According to research, NRC, the body’s first source of NAD+, may help with DNA repair, anti-aging, and metabolic health. [R]
NRC as Anti-Aging
Because NAD+ promotes many aspects of healthy aging, it has been proposed that Nicotinamide Riboside Chloride (NRC) possesses anti-aging qualities. Each of the cells has the helper molecule NAD+, which can be used to activate specific sirtuins and other enzymes that may aid in healthy aging. According to studies, sirtuins may restore DNA damage, increase stress resistance, lessen inflammation, and provide other advantages that support healthy aging. NRC, the body’s first source of NAD+, has been touted as a potential treatment for infertility, metabolic diseases, chronic illnesses, and healthy aging. It has been demonstrated that the NAD+ precursor (NMN) and NRC, a vitamin B3 derivative, can slow down the aging process. [R]
The information presented here is for educational purposes only and should not be construed as medical advice. NRC is intended for laboratory research use only and is not intended for human nicotinamide riboside supplementation and dietary supplements.
Potential Side Effects
- Nausea and digestive issues
- Skin problems such as itching and sweating
- Blood pressure becomes high
Where Can I Buy NRC online?
RCD.bio offers NRC for laboratory and research use only. Some company sell this as dietary supplement in crystal form with other ingredients: pullulan polysaccharide ,rice powder, bamboo extract powder, rice extract blend. It is important to note that RCD.bio sells this as research chemical thus the use of it as a supplement is not yet established
When buying NRC, it is important to choose a reputable market seller who provides quality NRC. At RCD.bio, customers can ensure each product is accompanied with a third-party-issued Certificate of Analysis showing the identification, purity, and concentration of our product. ,
Niacin is found in nicotinamide riboside chloride (NRC), which is also a precursor to nicotinamide adenine dinucleotide (NAD+), a compound that is involved in a number of metabolic processes in the body. The European Food Safety Authority (EFSA) has evaluated NRC for its safety and effectiveness in meal replacement products in crystal form and nutritional drink mixes, and it has given the product approval for usage for the general population. NRC may be advantageous for DNA repair, anti-aging, metabolic health, and immunological function. NRC may cause moderate and transient adverse effects such nausea, fatigue, headaches, indigestion, and skin issues, even though it is normally safe and well-tolerated at prescribed dosages. Before taking NRC, women who are pregnant or nursing should speak with their doctor. Overall, further research is needed to fully understand the mechanisms of action and potential side effects of NRC.
Please take note of the scientific applications of this product and carefully read our Terms and Conditions before making a purchase from RCD.bio. By completing your order and submitting payment, you agree to abide by our Terms and Conditions. Please be aware that the product packaging may differ slightly from the images displayed on our website.
If for any reason you are not completely satisfied with the product you receive, please contact us at [email protected]. Our team is dedicated to ensuring customer satisfaction and will be happy to assist you.
PLEASE NOTE: All products offered by RCD.bio are strictly intended for laboratory and research purposes only. They are not intended for use on animals or humans.