Noopept
Introduction
Noopept(N-phenylacetyl-l-prolylglycine ethyl ester) is a synthetic nootropic compound with remarkable cognitive-enhancing properties. Potency is one of the most intriguing features of Noopept. Despite being a synthetic derivative of another popular nootropic, Piracetam, Noopept exhibits its effects at concentrations approximately 1,000 times lower than Piracetam. This extraordinary characteristic has piqued the curiosity of researchers and sparked a growing interest in Noopept’s potential applications. This article will explore the fascinating world of Noopept, including its prospective benefits, and research applications. [R][R]
Studies suggest that Noopept may have a variety of advantageous effects. It has been found to have the potential to alleviate general irritability and anxiety, resolve sleep problems, and improve emotional stability in people with mild cognitive disorders.
However, it is important to reiterate that the use of Noopept should be strictly limited to research purposes, and its consumption by humans is not recommended. In the sections that follow, we will examine these studies in depth, casting light on the intriguing findings concerning Noopept’s effect on cognitive function.
Key Features of Noopept Powder
RCD.Bio offers Noopept with the following specifications:
- A purity of 98%, verified by third-party laboratory testing.
- Available in tablet form: 40mg/27ct/1080mg and 40mg/54ct/2.1g
Noopept
- CAS Number: 157115-85-0
- Molar Mass: 318.373 g·mol−1
- Chemical Formula: C17H22N2O4
- IUPAC Name: Ethyl 1-(phenylacetyl)-l-prolylglycinate
- Synonyms: N-Phenylacetyl-l-prolylglycine ethyl ester; GVS-111
How Noopept Works?
Although Noopept is predominantly recognized as a research chemical, its potential cognitive-enhancing properties have attracted attention. We discover a variety of potential mechanisms through which Noopept may manifest its effects, shedding light on its fascinating properties, by looking into its intricate mechanisms:
Potential increase in NGF and BDNF expression in the hippocampus
One of the remarkable findings surrounding Noopept is its potential to increase the expression of nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) in the hippocampus. NGF plays a vital role in the growth and survival of nerve cells responsible for transmitting touch and pain signals. On the other hand, BDNF is essential for the central nervous system’s capacity to learn and retain long-term memories. By potentially boosting NGF and BDNF expression, Noopept may contribute to improved cognitive function and neuronal health [R][R]
May improve the brain’s neuronal reaction to acetylcholine
Furthermore, Noopept shows promise in enhancing the brain’s response to acetylcholine, a neurotransmitter crucial for learning, memory, attention, and autonomic bodily processes. In animal models of passive learning avoidance, Noopept demonstrated an improved neuronal reaction to acetylcholine. This suggests that Noopept may enhance the brain’s ability to process and utilize acetylcholine, potentially leading to enhanced cognitive function and information retention [R][R]
May lower inflammatory cytokine levels
Another intriguing aspect of Noopept’s potential mechanisms is its potential to lower levels of inflammatory cytokines. In a rat model of acute exudative inflammation, Noopept administration significantly decrease quantity of interleukin-6 (IL-6) in the animals’ blood serum. Additionally, it reduced levels of another inflammatory cytokine called tumor necrosis factor-alpha (TNF-alpha) by a factor of two. By modulating inflammatory responses, Noopept may contribute to a more balanced immune system and potentially alleviate inflammatory conditions [R]
The scientific basis behind the benefits of Noopept
Numerous research investigations and trials on animals suggest that Noopept may have a number of benefits.
Inflammation
Noopept has been found to reduce inflammation in mice in a dose-dependent manner through various administration methods such as intravenous and oral dosing. Notably, Noopept exhibits anti-inflammatory properties by effectively decreasing chronic immunological inflammation, which refers to a prolonged state of inflammation within the immune system. This research provides valuable insights into Noopept’s potential as an anti-inflammatory compound. [R]
It is important to note that Noopept is intended for research purposes only and should not be used by humans.
Antioxidation
Noopept and Piracetam were evaluated in a cell-based study investigating the antioxidant properties of different supplements. The results of this study have revealed promising findings, suggesting that this dipeptide has the potential to be a therapeutic drug for treating diseases associated with an impaired endogenous antioxidant system. These findings highlight the significance of Noopept in the field of antioxidants and its potential implications for disease management.[R]
Anxiety
Anxiety can significantly impacts mental and emotional state. In recent years, there has been growing interest in finding effective ways to alleviate anxiety symptoms. One compound that has shown promise in this area is Noopept.
Data from comparative investigations suggests that Noopept may have a significant impact on reducing anxiety in test subjects with organic emotional liability and post-concussive syndrome, which refers to anxiety resulting from traumatic brain injury These investigations observed the effects of Noopept medication over a span of 56 days. Notably, it was found that the administration of Noopept led to a dramatic reduction in anxiety levels when compared to the baseline. This implies that Noopept may hold promise as a potential therapeutic option for individuals suffering from anxiety-related conditions. [R]
It is crucial to note that further research is needed to establish its efficacy and safety in humans.
Cognitive Disorder
Cognitive disorders, characterized by impairments in memory, concentration, and overall cognitive function, can significantly impact quality of life. Researchers have been investigating various compounds to identify potential interventions for cognitive disorders.A randomized comparative clinical investigation examined the effects of Noopept and Piracetam on two test subject populations with minor cognitive impairments, resulting from vascular and traumatic-related factors. The trial included a total of 53 test subjects, and the findings shed light on the potential benefits of Noopept in this context [R]
According to the study, test subjects receiving Noopept may have experienced improvements in several areas towards the end of the experiment. These areas include a reduction in weakness, irritability, and daytime sleepiness. Furthermore, individuals who took Noopept may have witnessed enhancements in their levels of anxiety and depression, as well as improvements in the depth and duration of their nocturnal sleep.
One noteworthy finding from the study is the potential improvement in concentration capacity among the test subjects receiving Noopept. It was observed that both long-term memory for past events and short-term memory for current events appeared to be enhanced. These prospective improvements were noticeable within the first two to three weeks of Noopept treatment, indicating an early positive impact on cognitive function
While these findings are encouraging, it is important to note that further research is necessary to establish the efficacy of cognition enhancing properties of Noopept.
Neuroprotection
Neuroprotection, the preservation of neuronal structure and function, is a key focus in research related to neurodegenerative diseases and conditions. Noopept, a popular nootropic compound, has drawn attention for its potential neuroprotective effects. studies investigating Noopept’s impact on neuroprotection, particularly in relation to Alzheimer’s disease and oxidative stress in cortical neurons. [R]
To evaluate Noopept’s neuroprotective potential, researchers created a cellular model of Alzheimer’s disease (AD) and conducted an investigation. The study findings suggest that Noopept may have the ability to shield PC12 cells from the detrimental effects of amyloid-beta, a peptide known to contribute to the progression of AD. This suggests that Noopept could potentially play a role in mitigating the negative impact of amyloid-beta, which is crucial in the context of neurodegenerative diseases. [R]
Another study explored Noopept’s neuroprotective effects on cortical neurons. The investigation focused on comparing its impact on both individuals with Down’s syndrome and healthy cortical neurons exposed to H2O2, a compound associated with oxidative stress. The findings indicate that Noopept might have the ability to prevent oxidative stress and apoptosis, a process of programmed cell death, in the cortical neurons [R]. Moreover, compared to Piracetam, another popular nootropic, Noopept demonstrated a stronger capacity for neuroprotection in this study.[R]
However, more comprehensive studies are required to establish the efficacy and long-term effects of Noopept as a neuroprotective compound.
Diabetes
Diabetes, a chronic metabolic disorder, affects millions of individuals worldwide. As researchers continue to explore novel treatment approaches, attention has turned to Noopept, a synthetic nootropic compound, and its potential effects on diabetes. This article delves into preclinical investigations that highlight Noopept’s impact on blood glucose levels, insulin resistance, and oxidative damage associated with diabetes.
In a preclinical investigation involving diabetic rats, treatment with Noopept demonstrated promising results in reducing blood glucose levels. Furthermore, the synthetic nootropic compound also exhibited a decrease in HOMA-IR (Homeostatic Model Assessment of Insulin Resistance) in the treated group of test subjects. This suggests that Noopept may have potential implications for pre-pubertal diabetic treatment by aiding in the regulation of blood glucose levels and improving insulin resistance. [R]
Another preclinical investigation focused on Noopept’s effects on diabetes-related complications, specifically oxidative hippocampus damage and discomfort. Diabetes mellitus, the most prevalent type of diabetes, is characterized by oxidative hippocampal neurotoxicity and neuropathic pain as primary symptoms. The study findings suggest that Noopept may have a role in reducing oxidative damage to the hippocampus and alleviating discomfort associated with diabetes [R]. These observations shed light on the potential neuroprotective properties of Noopept in mitigating diabetes-related complications.[R]
While these preclinical investigations provide valuable insights, it is crucial to conduct further research, including clinical trials involving human studies, to validate these findings and determine the safety of Noopept in managing diabetes.
Precautions
The FDA has not approved Noopept and has not reviewed it for safety or efficacy. [R]
This is not intended to be considered as medical advice and is only being supplied for educational purposes. Noopept are only to be used in labs and for study; they are not intended for human consumption.
Potential side effects
Noopept toxicity may potentially have unspecified side effects such as memory loss, headaches, gastrointestinal issues, and dizziness. [R]
Where Can I Buy Noopept online?
RCD.bio offers Noopept powder for laboratory research use only.
When buying Noopept, it is important to choose a reputable seller who provides quality Noopept. At RCD.bio, each product is accompanied with a third-party-issued Certificate of Analysis showing the identification, purity, and concentration of our product. You may also buy Noopept capsules as some offer it in as capsule form. Buy noopept powder at RCD.bio now!
Conclusion
Noopept is a synthetic nootropic compound that is comparable to Piracetam but requires much lower doses to manifest its effects.
Noopept has been studied for its potential benefits in reducing general irritation and anxiety, improving sleep, enhancing emotional stability, and addressing minor cognitive disorders. It is believed to work by increase quantity in expression of NGF and BDNF in the hippocampus, improving the brain’s neuronal response to acetylcholine, lowering inflammatory cytokine levels, and repressing the activity of stress-induced kinases.
However, it is important to note that Noopept has not been approved by the FDA and has not undergone extensive safety or efficacy evaluation. Potential side effects of Noopept may include memory loss, headaches, gastrointestinal issues, and dizziness, although individual experiences may vary.
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