One compound in the huge world of brain function support has recently attracted a lot of attention: NSI-189 Phosphate. The secret to increasing brain function and even promoting mental health may lie in this intriguing molecule. We shall go into the realm of NSI-189 Phosphate in this article and examine its scientific definition, its history of discovery, and its mechanism of action.

Before digging into the detailed overview and facts relevant to the product. It is important to make clear that NSI-189 Phosphate is only designed for scientific examination. It is expressly advised that this compound is not for human consumption. 

What is NSI-189 Phosphate?

Because of its possible neurogenic characteristics, NSI-189 Phosphate has piqued the interest of researchers. Simply put, it can alter the formation and development of nerve cells in the brain. This molecule belongs to the nootropics class of drugs, which are thought to have cognitive-enhancing properties. (R) (R)

The Discovery of NSI-189 Phosphate

The journey of NSI-189 Phosphate began in the laboratories of scientists who were intrigued by the brain’s remarkable capacity for growth and regeneration. These researchers set out to explore ways to stimulate neurogenesis, the process of generating new neurons or nerve cells in the brain. Emerging evidence also indicates that NSI-189 phosphate has regionally specific effects insofar as neurogenesis is observed largely in the subventricular zone of the hippocampus. (R) (R)

After years of intensive research, the team stumbled upon NSI-189 Phosphate, a compound that showed promise in enhancing brain health. They conducted numerous experiments and studies to understand its effects on brain function and mental well-being. (R)

The history of NSI-189 Phosphate involves various stages of scientific investigation, which include laboratory experiments, animal studies, and limited human trials. While the initial results have been encouraging, it is crucial to wait for further research and rigorous testing to determine its safety, efficacy, and potential benefits for human use.

Disclaimer: Before going into more detail about the possible advantages of NSI-189 Phosphate, it is critical to stress that further scientific study is required to completely comprehend its effects and establish its usefulness, and this research is only for educational reasons. The scientific history presented here is based on available information and may only encompass some of the compound’s discovery and development aspects.

The Potential Benefits of NSI-189 Phosphate

Enhanced Cognitive Function

Preliminary research suggests that NSI-189 Phosphate may have the ability to increase cognitive function, including memory, attention, and learning capacities. Animal model research has yielded positive findings, demonstrating improved cognitive function in a variety of activities. Cognitive tests such as Attention and Concentration: The Trail Making Test (Parts A and B), the Stroop Test, or the Continuous Performance Test (CPT) can evaluate attention, cognitive flexibility, and processing speed. These tests aim to assess attention, cognitive flexibility, and processing speed, which are crucial aspects of cognitive function. (R) (R)

Neurogenesis Stimulation

Powder NSI-189 is a benzyl piperazine-aminopyridine, a novel chemical entity that stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in the murine hippocampus in vivo. Animal studies have shown that this chemical can stimulate the growth of new nerve cells, perhaps leading to better brain health and function. While not extensively studied, there is some evidence that NSI augments endogenous repair mechanisms by increasing cell proliferation. (R) (R) (R)

Antidepressant Effects

Studies have shown that NSI-189 Phosphate may have antidepressant qualities. This chemical has shown promise in clinical trials involving subjects with major depressive disorder (MDD) in terms of lowering depressive symptoms and enhancing overall mood. (R) (R) (R)

Anxiety Reduction

NSI-189 Phosphate has also demonstrated the potential in reducing anxiety symptoms. According to research on animals, this substance may have anxiolytic properties that lessen anxiety and foster tranquility and relaxation. NSI-189 Phosphate has also demonstrated the potential to reduce anxiety symptoms. According to research on animals, this substance may have anxiolytic properties that lessen anxiety and foster tranquility and relaxation. (R)

Anti-Depressant Effects

The potential of NSI-189 phosphate in the treatment of cognitive diseases including Alzheimer’s disease and moderate cognitive impairment has been investigated in a preliminary study. Initial results suggest that this chemical may aid in reducing cognitive decline and cognitive enhancement performance in subjects with these disorders, while more research is required. (R) (R)

Potential Treatment for Cognitive Disorders

The potential of NSI-189 phosphate in the treatment of cognitive diseases including Alzheimer’s disease and moderate cognitive impairment has been investigated in a preliminary study. Initial results suggest that this chemical may aid in reducing cognitive decline and enhancing cognitive performance in subjects with these disorders, while more research is required. (R)

Disclaimer: The information provided about the potential benefits of NSI-189 Phosphate is based on available research and scientific studies. The potential benefits mentioned should not be interpreted as medical advice or a substitute for professional medical consultation. The information provided here is for educational purposes only and should not be relied upon as a sole source of information.

Key Features

Product Type: NSI 189 Phosphate Powder
Purity: 98%
Variants: Available in NSI 189 Powder (1000mg) in NSI 189 capsules (60caps/ 40mg/2.4g) in NSI 189 Liquid (30ml/33mg per ml/1000mg) (30ml/67mg per ml/2000mg)

CAS Number: 1270138-40-3
Molar Mass: 366.509 g·mol−1
Chemical Formula: C22H30N4O
IUPAC Name: (4-Benzylpiperazin-1-yl)-[2-(3-methylbutylamino)pyridin-3-yl]methanone (R)

How Does NSI-189 Work?

NSI-189 Phosphate is thought to exert its effects primarily through its ability to promote neurogenesis, which is the generation of new neurons in the brain. This compound is believed to stimulate the growth and development of nerve cells in specific regions of the brain associated with cognition, mood regulation, and overall brain function. (R)

By increasing neurogenesis, NSI-189 Phosphate may enhance the brain’s capacity to form new connections between neurons, strengthen existing neural networks, and have a significant improvement in communication among brain cells. This process is hypothesized to contribute to the potential cognitive-enhancing and mood-modulating effects associated with NSI-189 Phosphate. 

Also, it is thought that NSI-189 Phosphate affects several neurotransmitters and signaling pathways in the brain. It may affect the concentrations and activities of several neurotransmitters, including glutamate, dopamine, and serotonin, which are essential for controlling mood, motivation, memory, and learning. (R) (R)

It’s crucial to remember that while NSI-189 Phosphate illustrates a potential process, its actual use is still in progress. Although the substance has completed the preliminary investigation and early-stage clinical studies, regulatory authorities have not yet given it the go-ahead for general usage as a brain supplement.

Precautions to Consider

When considering NSI 189 Phosphate, it’s essential to be aware of certain precautions. Here are some important points to keep in mind:

  • Follow Instructions: Read and follow the provided instructions or any accompanying documentation.
  • Research Purposes: Recognize that the compound is only for laboratory research use and should not be utilized for self-administration or other non-research reasons.
  • Expert Guidance: Seek advice from experienced researchers, scientists, or medical experts in the field. Their knowledge may assist in ensuring optimal dosage, application, and safety measures.
  • Regulatory Compliance: Search for regulatory compliance such as the Food and Drug Administration (FDA) that may apply to the usage of the compound.
  • Handling and Storage: To preserve the safety and integrity of the compound, observe correct handling practices and store it in a cool, dry place to maintain its stability and prevent degradation. 
  • Safety and Disposal: Keep the compound out of reach of children to prevent accidental ingestion or exposure and follow recommended disposal methods.

Potential Side-effects of NSI 189- Phosphate

Although NSI-189 Phosphate shows promise as a supplement for the brain, it’s crucial to be aware of any possible adverse effects. It should be emphasized that experiences may differ and that the information currently available on side effects is based on limited research.

Subjects who have taken part in clinical studies or who have used NSI-189 phosphate have brought up specific negative effects. Gastrointestinal issues including nausea, upset stomach, or diarrhea may be among these adverse effects. There have also been reports of headaches, albeit these are usually minor and momentary. There are also mentioned experiences of sleeplessness or an increase in tiredness; however, further research is required to fully understand how NSI-189 Phosphate affects sleep habits. A few subjects have also noticed mood changes, such as an increase in irritation, anxiety, or emotional sensitivity. (R) (R)


  • NSI-189 Phosphate is a compound currently being studied for its potential cognitive-enhancing and mood-modulating effects.
  • It is believed to promote neurogenesis, the growth of new neurons in the brain, which may lead to improved brain function.
  • Research has explored its potential benefits in cognitive impairment, major depressive disorder (MDD), ischemic stroke, and diabetic neuropathy.
  • Studies suggest that NSI-189 Phosphate may have the potential to improve cognitive function, reduce depressive symptoms, aid in stroke recovery, and alleviate symptoms of diabetic neuropathy.
  • The compound’s exact mechanism of action is still being investigated, and it is thought to influence neurotransmitters and signaling pathways in the brain.
  • While NSI-189 Phosphate shows promise, it is essential to consider potential side effects such as gastrointestinal disturbances, headaches, sleep disturbances, and mood changes.
  • NSI-189 Phosphate is still undergoing research and development, and its safety, efficacy, and long-term effects require further investigation.

Buy NSI 189 Phosphate Online!

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NSI 189 Phosphate Powder (1000mg)
NSI 189 Phosphate Capsules (60caps/ 40mg/2.4g)
NSI 189 Phosphate Liquid (30ml/33mg per ml/1000mg) (30ml/67mg per ml/2000mg)


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