Oxytocin

Oxytocin has become a buzzword in recent years, touted as a cure-all for everything from social anxiety to relationship problems. But what exactly is oxytocin and what does it do? Let’s take a closer look.

The cyclic nonapeptide hormone oxytocin has the amino acid sequence CYIQNCPLG and also functions in the brain as a neurotransmitter. [R]Sir Henry Dale discovered in 1906 that extracts from the human posterior pituitary gland constrict a pregnant cat’s uterus. He gave the substance the name oxytocin (OT), which is derived from Greek words that signify “swift birth.” [R]

The posterior pituitary gland releases the hormone oxytocin into the bloodstream after it is created in the hypothalamus.  Oxytocin is a hormone that has been researched for its potential benefits, including reducing stress levels, promoting social bonding, and assisting with childbirth and breastfeeding. breastfeeding. It’s often called the “love hormone” or “cuddle hormone.” [R] While it is available as a research chemical, it’s important to note that it should not be used as a treatment without any proper research and professional guidance as rcd.bio only sells Oxytocin for laboratory use only

Key Features

rcd.bio offers Oxytocin with the following specifications:

  • A purity of 98%, verified by third-party laboratory testing.
  • Available in two dosages: 2mg and 5mg in powder form

How Oxytocin Works?

Oxytocin is a fascinating hormone that works in several ways to promote various physiological and behavioral processes. Oxytocin plays a role in interacting with the brain networks  [R] that process cues related to motivation. It specifically affects the dopaminergic activity of the mesocorticolimbic dopamine system, which is essential for motivation, motivated behavior, and affiliate behaviors.[R]

One of the most well-known functions of oxytocin is its ability to cause the muscles of the uterus and breasts to contract in women. This contraction is beneficial during labor and delivery, as well as during lactation, as it helps to promote milk letdown.  [R]Additionally, studies suggest that oxytocin release may have cerebral effects in the brain that regulate sexual behavior in male mammals, as well as peripheral effects on the smooth muscles of the male reproductive tract, aiding in sperm movement.[R] [R]

It’s worth noting that oxytocin is one of the few hormones that produces a positive feedback loop. This means that the rate of release of oxytocin increases as the concentration of oxytocin in the body increases. For example, more oxytocin is released when the uterus contracts during labor, which in turn leads to further contractions. [R]

The scientific basis behind the benefits of Oxytocin

Over the years, oxytocin peptide hormone has been the subject of numerous investigations in animals. The FDA has not given Oxytocin the go-ahead for human consumption, despite the fact that research suggests its enormous potential.

Sexual Arousal

Sexual arousal is a complex phenomenon that involves several physiological and psychological factors. Research has shown that oxytocin levels are associated with orgasm and sexual arousal in humans. A systematic review found that it is plausible to hypothesize a role for oxytocin in sexual desire given the sexual arousal induced by self-stimulation, in which sexual fantasies play a vital part.[R]

A study conducted in 1994 found that both men and women experienced increases in plasma oxytocin during orgasm. This strong association supports the idea that oxytocin may play a role in the sexual response. Additionally, another study’s findings provide further evidence that oxytocin significantly affects human sexual arousal.[R][R]

Further supporting the link between oxytocin and penile erection comes from a rat study. Male rats were found to experience penile erection and yawning after receiving oxytocin injections intracerebroventricularly (i.c.v.) at doses ranging from 5 to 90ng.[R]

Behavior

  • Trust
    It may play a significant role in social bonding and affiliation in mammals, according to research. It was discovered that administering OT intranasally significantly increases trusting behavior. Subjects who received OT seemed to be better able to get over barriers to trust. [R]
    According to a different study, administering it intranasally boosts people’s trust in one another, considerably enhancing the advantages of social contact. These findings are consistent with animal research that points to it as a crucial component of the biological underpinnings of pro-social behavior. [R]
    Researchers gave OT to participants in trust and risk-taking activities in order to establish a connection between OT and human trust. After receiving OT, participants with lower AQ (autism spectrum quotient) scores (less severe autistic symptoms) displayed more tendencies toward trusting behaviors than those with higher AQ scores. [R]
  • Romantic Bonding
    A total of four researchers were the only ones to measure or alter oxytocin and then observe behavior or subjective reactions associated with interpersonal bonding in adult romantic relations. [R]
    For instance, one of the four research finds a strong correlation between plasma OT and self-reported partner hugs. The study also discovered that premenopausal women with higher oxytocin levels and more frequent partner hugs have lower blood pressure and heart rates. [R]
    Another study’s results raise the possibility that oxytocin is crucial to the early phases of romantic connection. Researchers found that new couples had much greater OT levels than singles in their study. [R

Diabetes

A recent review article explored the role of oxytocin in diabetes and its associated complications. The article highlighted that oxytocin may have favorable metabolic effects due to its ability to alter insulin sensitivity, lipid profile, and glucose metabolism.

Research has shown that oxytocin can directly and indirectly affect insulin sensitivity and glucose uptake, indicating that it could be a potential strategy for treating diabetes by activating the oxytocin receptor system. In fact, randomized pilot clinical studies have demonstrated that oxytocin and its analogs can have positive effects on insulin sensitivity, weight management, and insulin secretion.

These findings suggest that the development of oxytocin and its analogs as therapeutic peptides for controlling diabetes is a promising possibility. With further research, oxytocin could play a vital role in the management of diabetes and its associated complications. [R]

Wound Healing

Higher OT levels were connected to more constructive communication behaviors, per a study done in 37 couples. Additionally, participants in the upper oxytocin quartile demonstrated quicker wound healing than those in the lower OT quartiles. [R]

Oxytocin has been found to have the power to repair wounds, according to a cell-based study. It was discovered that bacteria-triggered OT serves to activate transmitting transplantable wound healing potential to rats. [R]

Muscle Maintenance

As we age, our muscles lose strength and mass, a condition known as sarcopenia. However, recent research indicates that oxytocin (OT) plays a critical role in healthy muscle tissue homeostasis and regeneration. OT is produced in the hypothalamus and released into the bloodstream by the pituitary gland. It is known for its involvement in social bonding, but its function in muscle maintenance is less well-known.

A study found that the levels of oxytocin receptors in muscle stem cells decrease rapidly with age. Furthermore, a hereditary deficiency in OT can result in early sarcopenia. However, systemic short-term delivery of OT was shown to enhance muscle regeneration in elderly mice. These findings suggest that OT could be used to slow down or prevent skeletal muscle aging. OT analogs or agonists may potentially be used in the future as therapeutic peptides to promote muscle regeneration in elderly subjects.

Weight Loss

OT was generated in mice given a high-fat diet to make them obese in order to research its effects on lipid metabolism, boosting insulin sensitivity, and body weight. There was a dose-dependent reduction in body weight increase. In macrophages generated from M1, OT also reduced tumor necrosis factor-alpha (TNF-a). [R]

An Oxytocin analog with prolonged in vivo stability was shown in another investigation to decrease food intake and body weight in DIO rats. [R]

Heart Health

Studies have found that oxytocin can be good for the heart. It can help protect the heart against damage by producing special proteins that are important for heart health.[R]

In rats with heart damage, oxytocin has been shown to improve heart repair, reduce swelling, and make the heart work better. These findings suggest that oxytocin could be used as a treatment for heart disease.  [R]

Further research should be done on continuous OT administration and its effects on cardiac stem cells.

Precautions

The wrong amount of oxytocin can cause myocardial ischemia, severe tachycardia, and arrhythmias. Uterine rupture, hypertonicity, and spasms can be brought on by high oxytocin doses. If oxytocin is used in overly large doses or even slowly over the course of 24 hours, the drug may have an antidiuretic effect that causes extreme water intoxication, which may cause coma, seizures, or even the mother’s death. The risk of water intoxication and antidiuretic effects from exogenous oxytocin are higher in individuals who ingest fluids orally. [R]

Furthermore, this is not intended to be considered medical advice and is only being supplied for educational and scientific research. The products are only to be used in labs and for study; they are not intended for human consumption.

Potential side effects

The hormone oxytocin is produced naturally by the body and is also available in synthetic form for research purposes. Oxytocin is typically regarded as safe and well-tolerated when used in the authorized dosages. However, it could have adverse effects in certain people, just like any medication. Among oxytocin’s probable negative effects are the following: nausea and diarrhoea, headache, dizziness, abnormal heartbeat, modifications in blood pressure, allergic symptoms, including hives, itching, or breathing difficulties, and rapid weight gain. [R]

Where Can I Buy the Best Oxytocin?

rcd.bio offers oxytocin for laboratory research use only.

When buying oxytocin, it is important to choose a reputable seller who provides quality products. At rcd.bio, each product is accompanied with a third-party-issued Certificate of Analysis showing identification, purity, and concentration of our product.

RCB. bio does not sell intranasal oxytocin or oxytocin spray.

Conclusion

Oxytocin is a hormone released by the posterior pituitary gland that has a key role in uterine contractions during childbirth and milk letdown during breastfeeding in women. It also affects physiological and behavioral processes such as stress response, sexual reproduction, maternal-infant attachment, and social bonding. Oxytocin is commonly referred to as the “love hormone” or “cuddle hormone.” It interacts with brain networks that process motivation and affects the mesocorticolimbic dopamine system’s dopaminergic activity. Possible research areas may be to boost cognitive performance and behavior, diabetes, weight loss, wound healing and heart health. Oxytocin is generally safe and well-tolerated when used in the authorized dosages, but it could have adverse effects, such as nausea, diarrhea, headache, dizziness, and rapid weight gain. The FDA has approved oxytocin for specific uses during pregnancy and postpartum.

Disclaimer

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