Piperine 98%


Piperine 98% is an extract derived from black pepper (piper nigrum) that contains a high amount of the active compound piperine. Piperine is believed to enhance the intestinal absorption of various nutrients and compounds, including curcumin, the active ingredient in turmeric.

The alleged benefits of using Piperine 98% include improved bioavailability of health-promoting nutrients and compounds, such as antioxidants and anti-inflammatory agents. By increasing intestinal absorption, Piperine 98% may even help to maximize the benefits of various dietary supplements and natural remedies.

However, it is important to note that some sources of black pepper may contain pesticide residues, which could be harmful to health. Therefore, it is recommended to choose high-quality sources of Piperine 98% for one’s research studies to ensure its safety and efficacy.

Piperine 98% Product Details

Piperine 98% is a concentrated powder extract derived from the skin of the black pepper plant (piper nigrum L.). This off-white extract is gluten-free and is responsible for the characteristic flavor and aroma of black pepper. It is extracted using a process that isolates and concentrates the active compound piperine, which is known to have potential health benefits.

Research has suggested that piperine may have positive effects on nutrient absorption, reducing inflammation, and oxidative stress, making it potentially useful for people with certain health conditions. Black pepper extract also contains other nutrients like vitamins and minerals, contributing to its overall health-promoting effects.

  • CAS Number: 94-62-2
  • Molar Mass: 285.383 g/mol
  • Chemical Formula: C17H19NO3
  • IUPAC Name: (E,E)-1-[5-(1,3-Benzodioxol-5-yl)-1-oxo-2,4-pentadienyl]piperidine
  • Also known by Synonyms: Bioperine, piperoylpiperidine, 1-piperoylpiperidine, piperine

Key Features

  • 98% Purity
  • 10g | 20g
  • Sold for research purposes only

Potential Benefits of Piperine 98%

Piperine and Inflammation

Clinical trials have also demonstrated that piperine may have anti-inflammatory effects. In a trial of over 100 test subjects with type 2 diabetes or metabolic syndrome, the combination of curcumin and piperine was found to reduce CRP levels, highlighting the anti-inflammatory effects of the treatment. Similarly, in another trial, the combination reduced inflammation in patients with knee osteoarthritis. [R] [R]

Piperine and Drug Bioavailability

Several clinical trials have demonstrated that piperine can increase the availability of other substances, including nutrients and supplements. In two separate clinical trials, piperine increased the availability of carbamazepine, chlorzoxazone, and curcumin. These findings suggest that piperine may be useful for enhancing the body’s ability to use certain drugs and supplements. [R] [R] [R]

Piperine and Blood Sugar

Research on the effects of piperine on blood sugar levels is limited, but one clinical trial involving 100 people with type 2 diabetes reported a reduction in blood sugar levels and reduced liver damage with the use of piperine and curcumin. [R]

Piperine and Blood Cholesterol

Several clinical trials have investigated the effects of piperine on blood cholesterol levels. In one trial involving 118 people with type 2 diabetes, the combination of curcumin and piperine was found to lower total cholesterol and LDL (“bad”) cholesterol while increasing HDL (“good”) cholesterol. Another trial involving 100 patients with metabolic syndrome reported similar findings. [R] [R]

Piperine and Antioxidation

Research has shown that piperine may have antioxidant effects when combined with other compounds, such as curcumin. In several clinical trials, piperine and curcumin were shown to improve oxidative and inflammatory status in patients with metabolic syndrome, chronic lung disease, osteoarthritis, and pancreatitis. These findings suggest that piperine may be useful for improving antioxidant status in individuals with various health conditions. [R] [R] [R]

Piperine and Vitiligo

Finally, a clinical trial of 63 test subjects with vitiligo found that combined piperine and narrowband UV-B radiation therapy enhanced skin pigmentation. This suggests that piperine may be useful in the treatment of vitiligo. [R]

How It Works

Piperine 98% is a natural alkaloid extracted from black pepper. Its mechanism of action involves the prevention of certain enzymes responsible for the metabolism of other substances, resulting in increased bioavailability and absorption of nutrients and drugs. This increased absorption of nutrients and drugs makes it a valuable component in the management of several health conditions.

Scientific studies support the benefits of Piperine 98% in enhancing the effectiveness of certain drugs such as carbamazepine and chlorzoxazone, by increasing their bioavailability. Additionally, Piperine 98% has been found to support the absorption of other nutrients such as resveratrol, a potent antioxidant found in red wine, which is known to support heart health. Piperine 98% has also been shown to aid in the absorption and processing of certain foods, making it an essential spice for culinary purposes.

In addition to its absorption-enhancing effects, Piperine 98% has been linked to several health benefits, including its ability to support the control of inflammation, blood sugar, and blood cholesterol levels. Piperine 98% has also been found to enhance the antioxidant capacity of the body, which can support overall health.

Moreover, Piperine 98% has been found to have heat-generating properties, making it useful in weight management as it can increase the body’s metabolic rate. Its ability to enhance the bioavailability of nutrients and drugs makes it a valuable component in the management of several health conditions, including metabolic disorders, joint inflammation, and skin disorders.


Test subjects with certain health conditions or diseases should exercise caution or avoid using Piperine 98%. While the compound has shown potential health benefits, it is important to note that it is not a cure or treatment for any disease or health condition.

Clinical participants who are taking prescription medication or have a chronic disease or health condition should consult their doctor before using Piperine 98% or any supplement containing black pepper extract powder.

Furthermore, it is essential to read and follow the labels on any research chemical containing Piperine 98%.

Finally, while Piperine 98% may provide health benefits, it is not a cure for any disease or health condition.

Potential Side Effects

Piperine 98% may cause gastrointestinal distress, such as nausea, vomiting, and diarrhea. Piperine may also interact with certain medications, so it is important to consult a healthcare provider before using it if you are taking prescription medication.

Additionally, pregnant and breastfeeding women should avoid ingesting Piperine 98% as there is not enough research to determine its safety in these populations.


In conclusion, Piperine 98% is a promising compound extracted from black pepper that offers numerous benefits to customers. It has been shown to improve the intestinal absorption of nutrients, enhance the bioavailability of certain drugs, and support healthy inflammation and oxidation levels.

Additionally, it can lower cholesterol, reduce blood sugar, and support liver function. When purchasing Piperine 98%, it is important to buy from a reputable site that complies with FDA regulations and offers safe shipping and handling.

Piperine 98% can be used in cooking to add heat and flavor, making it a potential addition to any store or food business. However, more studies are needed to verify this.

While it is not intended to treat or cure any disease or health condition, Piperine 98% is being investigated for its supposed range of potential health benefits.


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PLEASE NOTE: All products offered by rcd.bio are strictly intended for laboratory and research purposes only. They are not intended for use on animals or humans.