RU-58841 is a particular chemical, commonly referred to as a nonsteroidal anti-androgen receptor modulator, that has shown potential in promoting hair growth, treating hair loss, and improving hair density. Initially researched as a treatment for androgenetic alopecia and androgenic alopecia, the compound works by blocking DHT receptors in the scalp, leading to increased human hair production.
RU-58841 Product Details
RU 58841 is a research chemical developed in the 1980s as a potential topical treatment for androgenic alopecia, also known as rapid hair loss. It is clinically categorized as a specific androgen receptor antagonist. RU 58841 is currently only available for laboratory and research use.
- CAS Number: 154992-24-2
- Molar Mass: 369.41 g/mol
- Chemical Formula: C17H18F3N3O3
- IUPAC Name: 1-[(4R,6S)-6-[4-(1H-benzimidazol-2-yl)phenyl]-2,2,2-trifluoro-5-hydroxyhexyl]-1H-pyrrole-3-carboxamide
- Also Known by Synonyms: PSK-3841, HMR-3841, 5α-Reductase inhibitor RU58841, RU-58841.
- 98 % Purity
- Potential topical treatment for certain disorders
- Sold for research purposes only
Potential Benefits of RU-58841
Potential Treatment for Androgenic Alopecia
RU 58841 is a chemical that prevents DHT from binding to androgen receptors in the hair follicle, thereby preventing hair loss and promoting hair growth. According to a laboratory study published in the Journal of Investigative Dermatology, RU 58841 was found to promote hair growth in balding scalp grafts maintained in mice. [R]
Similarly, a clinical trial conducted in 2014 reported that topical application of RU 58841 for 6 months resulted in a significant increase in hair diameter and hair density in male patients with androgenic alopecia. [R]
Treatment for Androgenic-Dependent Skin Disorders
RU 58841 has also been investigated for its potential use in treating other androgenic-dependent skin disorders, such as acne and hirsutism. A laboratory study published in the Journal of Dermatological Science demonstrated that RU 58841 reduced sebum production and decreased cellular proliferation in sebocytes, indicating that it may be a useful treatment for acne. [R]
Similarly, a study published in the European Journal of Dermatology found that topical application of RU 58841 reduced hair growth in hirsute women. [R]
Potential to Improve Body Hormone Levels
RU 58841 has been shown to inhibit DHT binding to androgen receptors not only in the hair follicle but also in other parts of the body, such as the prostate gland. In a laboratory study published in the Journal of Steroid Biochemistry and Molecular Biology, RU 58841 was found to reduce the size of the prostate gland in castrated rats. [R]
This suggests that RU 58841 may have potential as a treatment for benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland. [R]
Topical Alternative to Oral Finasteride
RU 58841 may be a potential alternative to oral finasteride, a medication commonly used to treat androgenic alopecia and BPH. Oral finasteride can have adverse effects on body hormone levels, such as decreased libido and erectile dysfunction. [R]
In a clinical trial published in the Journal of the American Academy of Dermatology, topical application of RU 58841 was found to be as effective as oral finasteride in promoting hair growth and reducing hair loss, but without adverse effects on body hormone levels. [R]
How It Works
RU 58841 is a non-steroidal anti-androgen that has shown promising results in encouraging average hair growth. It functions by blocking androgen receptors, particularly those in the hair follicle, and inhibiting the binding of DHT (dihydrotestosterone) to these receptors. As a result, it reduces the so-called “miniaturization process,” which leads to hair thinning and baldness in androgenic alopecia.
RU 58841 is available in both solid and solution form and is commonly used as a topical anti-alopecia agent. In laboratory experimentation, allegedly promotes hair growth and increases hair diameter. Some studies claim that the chemical can maintain balding scalp grafts, suggesting that it may be effective in reversing hair loss in both men and women.
When compared to topical finasteride, another commonly used anti-androgenic treatment for hair loss, RU 58841 has been shown to have similar, if not superior, effects on hair growth. Studies have also demonstrated that RU 58841 promotes cellular proliferation in the hair follicle matrix cells and lengthens the anagen phase while shortening the telogen phase, leading to an increase in hair growth.
The scientific basis behind the benefits of RU 58841 lies in its ability to block androgen receptors, which play a crucial role in the pathogenesis of androgenic alopecia. Reducing the levels of DHT and androgen concentration in the hair follicle enables the follicle to remain in the growth phase for longer periods, promoting normal hair growth and improving hair diameter.
Overall, the mechanism of action of RU 58841 in the human body shows promise in treating androgenic alopecia and other androgenic-dependent skin disorders. Clinical trials are still ongoing to determine the long-term effects and potential side effects of this research chemical.
As RU 58841 for sale is a research chemical and not yet approved for human use, it is not guaranteed to be safe for topical application in humans. It should only be used in a laboratory setting and should not be used by individuals who are not trained in handling research chemicals.
It should be stored at room temperature and handled with caution. It is important to note that the effects of long-term exposure to RU 58841 are not fully understood, and it is not recommended for topical use on humans until it has been thoroughly studied and proven safe.
Potential Side Effects
As RU 58841 is a research chemical, its safety and potential side effects in humans are not fully understood. Some studies have suggested that RU 58841 may cause slight hair shedding or itching, but these effects are generally mild and temporary. It is important to note that RU 58841 should not be ingested and should only be used topically.
As with any research chemical, it should be handled with care, stored properly at room temperature, and used in accordance with safety guidelines.
In conclusion, RU 58841 has shown promising benefits as a potential treatment for androgenic alopecia and androgen-dependent skin disorders. As a non-steroidal topical androgen antagonist, it has been shown in laboratory research and clinical trials to promote hair growth and increase hair diameter.
Our company is committed to providing quality RU 58841 for research purposes with great customer service and fast shipping. Although more research is needed to fully understand its effectiveness, RU 58841 represents a promising development in the field of topically applied hair growth treatments.
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