S-Acetyl L-Glutathione


S-Acetyl L-Glutathione, also known as S-A-GSH or S-Acetyl Glutathione, is a naturally occurring form of glutathione that acts as a potent antioxidant in the body. It is the only intracellular glutathione, and its bioavailability decreases over time until it reaches nearly no bioavailability.

Glutathione is a crucial molecule that supports the health of neurons, liver, and immune system function. Research is underway to investigate the potential applications of S-Acetyl L-Glutathione among most glutathione supplements.

However, it is important to note that dietary supplements containing S-A-GSH have not been proven safe for human consumption, and more research is needed to establish their safety and efficacy. Therefore, we recommend purchasing S-Acetyl L-Glutathione products for research purposes only.

S-Acetyl L-Glutathione Product Details

S-Acetyl L-Glutathione is a specialized form of glutathione that has been modified through acetylation. Glutathione is a naturally occurring molecule that is essential for promoting healthy aging and supporting various biological functions in the body. However, traditional forms of glutathione supplements may not have optimal bioavailability, which can limit their effectiveness.

S-Acetyl L-Glutathione was developed to overcome this issue by improving its bioavailability and ensuring that cells receive the glutathione they need.

The research chemical is believed to improve S-G-ASH’s bioavailability and may even increase glutathione levels. Thus, it could be an effective option for supporting healthy aging and various biological functions in the body.

Key Features

  • 98% Purity
  • 5g
  • Could possibly cross blood-brain barrier
  • Sold for research purposes only

Potential Benefits of S-Acetyl L-Glutathione

S-Acetyl L-Glutathione, also known as SAG or S-A-GSH, refers to a form of glutathione that is believed to increase glutathione levels within cells, resulting in several health benefits. Glutathione is an essential molecule for the body that supports liver function, immune system health, and neuron well-being, among other functions.

Here are some possible applications of S-Acetyl L-Glutathione:

May Improve Insulin Sensitivity

Studies have found that people with insulin resistance have lower glutathione levels, especially if they have complications like neuropathy or retinopathy. When glutathione levels increase, insulin sensitivity can improve, leading to better glucose control. [R] [R]

May Reduce the Impact of Diabetes

Studies suggest that glutathione supplements may decrease oxidative stress and damage in people with uncontrolled diabetes. This could be due to the role of glutathione in increasing insulin sensitivity, a crucial factor in the management of type 2 diabetes. [R]

May Promote Healthy Liver Function

Studies have found that S-Acetyl L-Glutathione may protect the liver against oxidative damage caused by substances like carbon tetrachloride (CCl4). S-Acetyl L-Glutathione appears to reduce reactive oxygen species (ROS) generation and inhibit pro-inflammatory signaling by deactivating TLR4/NF-B signaling. Therefore, S-Acetyl L-Glutathione might be a potential hepatoprotective agent to prevent oxidative liver damage. [R]

May Reduce Symptoms of Parkinson’s Disease

Glutathione appears to play a role in treating Parkinson’s disease symptoms and supporting neuron health. Some research suggests that injected glutathione may be an effective therapy, but there is limited evidence supporting the use of oral glutathione supplements. [R]

May Act as an Effective Antioxidant

S-Acetyl L-Glutathione is a potent intracellular antioxidant that fights free radicals and protects the body from their harmful effects. It can reduce oxidative stress and inflammation, which are linked to several chronic diseases. [R]

However, while these studies show the potential health benefits of S-Acetyl L-Glutathione, more research is needed to determine the safety and efficacy of research chemicals containing this molecule.

How It Works

Many research groups consider S Acetyl L Glutathione as an efficient antioxidant that the body produces naturally. It consists of an acetyl function group that enhances its bioavailability and ability to cross the blood-brain barrier. The glutathione molecule is essential for maintaining optimal health as it is involved in many physiological processes.

One of the alleged benefits of S Acetyl L Glutathione is its ability to support neuron health. The glutathione molecule is abundant in neurons, and it helps protect them from oxidative stress and inflammation. S Acetyl L Glutathione also shows an ability to penetrate the blood-brain barrier and remain intact, making it an effective way to increase glutathione levels in the brain.

S Acetyl L Glutathione also plays a crucial role in liver health. The liver is responsible for detoxifying the body, and glutathione is a crucial molecule in this process. S Acetyl L Glutathione helps the liver remove toxins by supporting the production of glutathione in the liver cells.

When S Acetyl L Glutathione is ingested, the body begins to break it down into its constituent parts, which include glutathione and an acetyl group. The acetyl group enhances the bioavailability of glutathione, allowing it to enter cells more easily. Once inside the cell, glutathione supports cellular health by protecting mitochondria from oxidative stress.

There is scientific evidence that suggests S Acetyl L Glutathione may have the potential to cure certain skin conditions. Glutathione is a key molecule in the production of melanin, the pigment that gives skin its color. S Acetyl L Glutathione helps to increase the production of glutathione, which may result in a more even skin tone.


S Acetyl L Glutathione is generally considered safe for most test subjects. However, the research compound may still carry risks to certain groups.

Those with zinc deficiency should avoid long-term supplementation of S Acetyl L Glutathione as it may further deplete zinc levels in the body. It is also important to note that S Acetyl L Glutathione should not be used to diagnose, treat, or cure any medical condition.

Potential Side Effects

There are no known side effects associated with short-term use of S Acetyl L Glutathione. However, long-term supplementation has not been evaluated thoroughly enough to determine its safety. Additionally, clinical participants with zinc levels that are too low may not benefit from S Acetyl L Glutathione supplements.

As with any research compound, it is always best to buy S Acetyl L Glutathione for scientific research only.


In conclusion, S Acetyl L Glutathione is a potent antioxidant that could support immune system health, promote liver health, and aid in maintaining neuron health. It is known for its low bioavailability and is not easily obtained from dietary sources. The body produces glutathione, but the exact amount may vary, and lower zinc levels can affect its production.

S Acetyl L Glutathione research compounds should be purchased for research studies alone


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