Sarcosine, an amino acid derivative, plays a pivotal role in brain health and has gained recognition as a potential dietary supplement. One of its key benefits lies in its interaction with NMDA receptors, which are essential for cognitive function. Sarcosine acts as a modulator for these receptors, potentially enhancing synaptic signaling and promoting better brain health.

Furthermore, research has explored the potential of sarcosine as a complementary treatment for schizophrenia. It is believed that by modulating NMDA receptors, sarcosine may help alleviate some of the symptoms associated with this mental disorder, offering hope for improved test subject outcomes.

This information is for research purposes only and should not be considered medical advice. This product is not intended to diagnose, treat, cure, or prevent any disease. Always consult with your healthcare provider for personalized recommendations and guidance regarding the use of Sarcosine a vitamin or any other medication.

Sarcosine Product Details

Sarcosine, also known as N-methylglycine, is a significant compound involved in glycine synthesis and degradation. It acts as an intermediary and byproduct in these processes, with enzymes like sarcosine dehydrogenase converting it into glycine and glycine-N-methyl transferase generating sarcosine from glycine. This natural amino acid derivative has diverse physiological roles.

Sarcosine’s impact extends beyond biochemical pathways; it serves as a competitive inhibitor of the type I glycine transporter (GlyT1) and acts as an N-methyl-D-aspartate receptor (NMDAR) co-agonist, potentially influencing memory and concentration. As part of one-carbon metabolism, it holds promise for potentially enhancing focus and mood through its multifaceted interactions within the body.

Sarcosine plays a significant role in the metabolism of S-adenosyl-methionine (SAMe). SAMe is a crucial methyl donor in various biochemical reactions within the body, including methylation reactions that are essential for DNA, RNA, protein, and lipid synthesis, as well as neurotransmitter metabolism.

Moreover, ongoing research explores sarcosine’s therapeutic potential, particularly in addressing conditions such as schizophrenia, where it may alleviate symptoms and improve mental well-being. Additionally, its investigation as a potential biomarker for prostate cancer underscores its expanding clinical relevance, prompting further examination of its diverse applications and benefits.

Sarcosine is also known as n-methylglycine, sarcosinic acid, methylaminoacetic acid, methylglycine, glycine, n-methyl-, n-methylaminoacetic acid, 2-(methylamino)acetic acid, sarcosin, (methylamino)acetic acid, (methylamino)ethanoic acid and sargosine hydrochloride.

Its molecular formula is C3H7NO2.

Key Features

  • 98% Purity
  • 50g Sarcosine Powder
  • Sold for research purposes only and cannot be used as prescription drugs

Potential Benefits of Sarcosine Powder

Potential Treatment for Schizophrenia

One of the primary applications of Sarcosine Powder is in treating schizophrenia. Research has shown that schizophrenia is linked to malfunctioning NMDA and glycine receptors. Clinical trials have demonstrated its potential effectiveness when used in combination with other antipsychotics for treating this condition. Participants receiving sarcosine treatment exhibited significant improvements in their overall psychiatric symptoms. [R]

Potential for Depression

While primarily considered an antipsychotic, Sarcosine Powder also shows potential in addressing depression symptoms, especially in the context of schizophrenia. Recent research has highlighted the role of the NMDA receptor in Major Depressive Disorder, and sarcosine’s influence on this receptor may offer therapeutic benefits. Some trials in both rodent models and participants have indicated that sarcosine may improve depression-like behaviors. [R]

OCD Management

Sarcosine Powder might also help manage obsessive-compulsive behaviors, possibly through its impact on NMDA and glycine channels in the brain. Current research suggests a significant role of the NMDA system in OCD. A study involving OCD participants on sarcosine treatment demonstrated rapid therapeutic effects, supporting the glycine transporter-1 as a potential target for OCD treatment. [R]


Sarcosine Powder’s neuroprotective properties are evident in its ability to possibly prevent damage from conditions like stroke. Research has shown that it may protect against damage caused by transient ischemic attacks (stroke) in animal models, possibly through its inhibitory effects on glycine receptors. Moreover, there is evidence that sarcosine may mitigate the neurotoxicity induced by NMDA antagonists like glutamate, which can damage neurons over time. Sarcosine’s ability to modulate levels of such neurotransmitters indicates its potential for neuroprotection. [R]

While these findings offer promising insights into the potential benefits of Sarcosine Powder, further research is essential to validate and expand upon these applications. Nonetheless, the existing studies provide a compelling basis for considering Sarcosine Powder as a compound to support various aspects of mental and neurological well-being, potentially improving the quality of life for those facing these conditions.

How It Works

Sarcosine’s mechanisms of action, as found in various studies, are thought to revolve around its influence on two crucial receptors within the brain.

Firstly, it activates the NMDAR, or N-methyl-D-aspartate receptor, much like glycine does. This activation occurs through a process in which both glycine and glutamate are involved, effectively increasing the NMDAR’s activity. This mechanism is believed to underlie the therapeutic effects of sarcosine in conditions like schizophrenia and other mental health disorders.

Secondly, sarcosine blocks the GlyT1 transporter, which is responsible for regulating glycine levels in the brain. By inhibiting this transporter, sarcosine allows glycine to accumulate in the brain. This accumulation, in turn, may lead to increased NMDAR activity. This dual action of activating NMDAR and blocking GlyT1 potentially contributes to alleviating symptoms associated with mental health disorders, including schizophrenia.

In essence, sarcosine’s effects on these receptors, as observed in cell studies, suggest its role in modulating neurotransmitter activity and maintaining the delicate balance of chemicals like glycine and glutamate in the brain, which may be pivotal for improving mental health.


When researching the use of Sarcosine Powder, it is essential to take certain precautions. Here are some precautions to keep in mind:

Observe best practices for studying research chemicals

Studying research chemicals requires a responsible and informed approach to ensure safety and meaningful scientific exploration. Research chemicals, also known as designer drugs or experimental compounds, are substances synthesized for scientific investigation or exploration of their properties.

Follow the recommended dosage in the warning section

Adhere to the recommended dosage instructions outlined on the product label. Avoid a significant increase of the suggested dose to minimize the risk of potential adverse effects among test subjects.

Potential Side Effects

Sarcosine is generally considered safe when used within recommended dosages. Clinical trials and research studies have reported minimal side effects associated with possible sarcosine supplementation. Commonly reported side effects include mild gastrointestinal discomfort, such as nausea or diarrhea, although these effects are typically transient and diminish with continued use. Additionally, there have been no significant adverse effects noted in studies, suggesting a favorable safety profile.


In conclusion, Sarcosine Powder offers a range of benefits that may significantly impact brain health and overall well-being. Its ability to modulate NMDA receptors, much like serine and S-adenosyl methionine, has been evaluated in clinical studies and positive effects have been noticed by customers who have started incorporating it into their daily routines. It helps to treat conditions like schizophrenia and depression to potentially aid in the management of obsessive-compulsive behaviors, Sarcosine Powder shows promise as a potentially versatile supplement.

By shopping online, customers can save time and money when purchasing this research chemical, with the convenience of same-day shipping ensuring swift delivery. While it may not be a cure for every ailment, Sarcosine Powder has earned positive reviews for its potential to diagnose and alleviate symptoms associated with mental health disorders. Continuing to explore its diverse applications in the realm of brain health, this vitamin-like compound holds the potential to offer renewed energy, focus, and support in the ongoing battle against the disease.


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