SR-9011 is a synthetic compound primarily intended for laboratory research use. It falls into the category of research chemicals and is not approved for human consumption. This compound is designed to interact with the body’s circadian rhythms and cell metabolism, and it has gained attention for its potential benefits in enhancing muscular and cardiovascular endurance while also potentially influencing fat loss.

One of the key aspects of SR-9011 is its ability to modulate circadian rhythms. It works by activating certain nuclear receptors in the body, which are responsible for regulating genes involved in the circadian clock. This can lead to improvements in the synchronization of various physiological processes with the body’s internal clock, potentially optimizing performance during specific times of the day.

SR-9011 Product Details

SR-9011, a research chemical often confused with a selective androgen receptor modulator (SARM), stands apart due to its classification as a rev erba agonist. It operates by enhancing the activity of the naturally occurring Rev-ErbA protein within our bodies. This augmentation of Rev-ErbA triggers a range of physiological processes, including the promotion of lipid and glucose metabolism and the inhibition of fat cell growth.

It is crucial to differentiate between a rev erb α agonist and a selective androgen receptor modulator. Unlike SARMs, which activate androgen receptors primarily in muscle and bone tissues, mimicking the effects of testosterone and creating an extremely anabolic environment for building lean muscle and improving physical performance, SR 9011 follows a different path. Its influence is not directed at androgen receptors but rather amplifies the inherent circadian rhythm orchestrated by the rev erbα protein. Therefore, SR-9011’s classification as a SARM is a common misconception due to its unique mode of action.

SR 9011 has the potential to enhance immune response and increase skeletal muscle oxidative capacity. Additionally, it may offer benefits to potentially improve hyperglycemia, which is elevated blood sugar levels and could be explored in conditions like neuroinflammatory diseases and myocardial infarction.

  • CAS Number 1379686-29-9
  • Molar Mass 479.04g·mol−1
  • Chemical Formula C23H31CIN4O3S
  • IUPAC Name 3-4-chlorophenyl methyl-5-nitrothiophen-2-yl methyl amino methyl -N-pentylpyrrolidine-1-carboxamide

Key Features

  • 30ml | 1000mg
  • 98% Purity
  • Sold for research purposes only

Potential Benefits of SR-9011

Potential Enhanced Muscular Endurance

SR-9011 has shown a potential to improve muscular endurance in laboratory research studies. By influencing gene expression related to energy metabolism, it may lead to better utilization of energy sources during physical activity. [R]

In a study published SR 9011 was found to increase skeletal muscle oxidative capacity in animal studies. This effect could translate into greater stamina and prolonged exercise performance. [R]

Potential Cardiovascular Endurance

Laboratory research suggests that SR 9011 might enhance cardiovascular endurance. By optimizing circadian behavior and metabolic processes, it could improve the heart’s ability to handle prolonged physical exertion. [R]

A study published in the Journal of Applied Physiology demonstrated that SR 9011 supplementation in mice improved their running capacity, which is indicative of enhanced cardiovascular endurance. [R]

Potential for Improved Hyperglycemia

SR-9011 has been investigated for its ability to potentially improve hyperglycemia, a condition characterized by elevated blood sugar levels. This research is primarily conducted in animal models. [R]

In a study conducted on diabetic mice, published in the journal Diabetologia, SR 9011 was found to regulate glucose metabolism and reduce hyperglycemia, suggesting its possible utility in managing blood sugar levels. [R]

Neuroinflammatory Diseases

Some preclinical studies have explored SR-9011’s potential effect on neuroinflammatory diseases. While not definitive, this research indicates that it may have a role in modulating inflammation in the central nervous system. [R]

One study published in Frontiers in Aging Neuroscience investigated the potential neuroprotective effects of SR 9011 in a mouse model of Alzheimer’s disease, suggesting that it could mitigate neuroinflammation and cognitive decline. [R]

Myocardial Infarction

Clinical studies have examined SR-9011’s impact on myocardial infarction (heart attack). Studies in animal models have suggested that it might have protective effects on heart disease by reducing oxidative stress and inflammation. [R]

A study published in the Journal of Cellular and Molecular Medicine found that SR-9011 treatment in rats subjected to myocardial infarction reduced cardiac injury markers and improved heart function. [R]

It’s important to note that while these laboratory research findings are promising, SR-9011’s safety and efficacy in humans are not fully understood, and further clinical research is necessary to determine its potential benefits and risks in clinical settings. Additionally, the use of SR-9011 for human consumption is not approved or recommended at this time, and it remains a subject of scientific investigation.

How It Works

SR-9011 operates through a distinctive mechanism of action centered around its interaction with the Rev-ErbA protein, which naturally occurs in the human body. As a Rev-ErbA agonist, SR 9011 binds to and activates this nuclear receptor protein. This activation plays a pivotal role in modulating circadian rhythms, the body’s intrinsic 24-hour cycles that govern various physiological processes. By synchronizing these processes with the circadian rhythm, SR-9011 impacts critical functions like sleep-wake patterns, metabolism, and hormone regulation.

Furthermore, SR 9011’s influence extends to metabolic processes, where it can enhance lipid and glucose metabolism. This effect has the potential to improve blood sugar control and promote the efficient utilization of fats as an energy source. Additionally, SR 9011 has been observed to inhibit the growth of fat cells, potentially contributing to reduced overall body fat.

In the context of physical performance, SR-9011’s modulation of circadian rhythms and the body’s metabolism may translate into enhanced exercise capabilities and endurance. Optimizing the timing of energy utilization could improve both muscular and cardiovascular endurance during physical activities. However, it is crucial to note that while these effects have been demonstrated in preclinical studies and animal models, the safety and efficacy of SR 9011 in humans require further investigation.


When researching the use of SR-9011, it is essential to take certain precautions. Here are some precautions to keep in mind:

Observe best practices for studying research chemicals

Studying research chemicals requires a responsible and informed approach to ensure safety and meaningful scientific exploration. Research chemicals, also known as designer drugs or experimental compounds, are substances synthesized for scientific investigation or exploration of their properties.

Follow the recommended dosage in the warning section

Adhere to the recommended dosage instructions outlined on the product label. Avoid a significant increase of the suggested dose to minimize the risk of potential adverse effects among test subjects.

Potential Side Effects

The extended-term adverse outcomes of SR-9011 have not been definitively determined in clinical studies, primarily owing to the limited extent of research conducted. Nonetheless, anecdotal accounts have hinted at a possible side effect related to insomnia, which may be linked to its ability to induce increased hyperactivity.


In conclusion, SR9011, classified as a research chemical intended primarily for laboratory research use, has shown promise in various cellular and physiological contexts. The compound’s short half-life and potential benefits, such as weight loss and enhanced circadian rhythm modulation via Rev-ErbA receptors, have piqued scientific interest. Research, notably under the guidance of experts like Professor Thomas Burris, has explored its impacts on diverse cell types, including cancer cells, normal cells, and immune cells.

Studies into SR9011’s anticancer activity offer intriguing data, with researchers investigating its potential role in inhibiting cancer progression. However, due to the complexities of cancer biology, further research is essential to delineate its precise mechanisms and therapeutic applications.

Additionally, SR9011’s suitability for laboratory research mandates appropriate institutional animal care, adherence to the Animal Welfare Act, and stringent cell-based studies. Its sensitive nature, characterized by an amino methyl n pentyl structure, necessitates proper handling, including storage in a tightly sealed container, ideally in a cool, dry place, to maintain its integrity.

While SR9011’s suppliers’ fast shipping availability is advantageous for researchers, the compound’s effects on various bodily systems, including the brain, liver, cholesterol regulation, and even breast cancer, warrant careful investigation. In summary, SR9011 presents a compelling avenue for exploration in laboratory research, but its full potential and implications are yet to be unveiled through rigorous scientific inquiry.


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