Uridine monophosphate disodium (UMP disodium) is a nucleotide that is used as a monomer in RNA. It is a chemical compound derived from ester of phosphoric acid with the nucleoside uridine and consists of the phosphate group, the pentose sugar ribose, and the nucleobase uracil. UMP disodium has been studied for its potential cognitive enhancing properties, improving sleep quality, relieving nerve pain, reducing the symptoms of lung diseases, and relieving depression and bipolar disorder. However, more research is needed to confirm these effects. Some potential side effects of UMP disodium include headaches, nausea, vomiting, diarrhea, abdominal cramps, indigestion, vivid dreams, and fever at high doses. It is important to consult with a healthcare professional before taking UMP disodium, especially if you have any underlying health conditions or are taking other medications or supplements. [R] [R] [R]

The nucleotide uridine monophosphate disodium (UMP disodium) is essential for numerous biological functions. It is a significant part of ribonucleic acid (RNA) and is an ester of phosphoric acid with the nucleotide uridine. UMP, also known as ribonucleotide monophosphate, is composed of a phosphate group, the pentose sugar ribose, and the nucleobase uracil. Pyrimidines are necessary for the synthesis of both DNA and RNA and are produced by UMP, which also serves as a monomer in RNA. UMP’s potential benefits for cognition and neuroprotection have been researched in brain science. Supplements for the diet and natural sources also include it. [R] [R] [R]

Key Features of Uridine Monophosphate Disodium

RCD.Bio offers Uridine monophosphate disodium with the following specifications:

  • A purity of 98%, verified by third-party laboratory testing.

Uridine monophosphate disodium [R]

  • CAS Number: 3387-36-8
  • Molecular weight: 368.14 g/mol
  • Chemical Formula: C9H11N2Na2O9P
  • Synonyms:Uridine 5′-monophosphate disodium salt
  • IUPAC Name: disodium;[(2R,3S,4R,5R)-5-(2,4-dioxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate

How It Works

UMP-Disodium, a substance made from uridine, may influence cognitive function in a number of ways. The first function is that it acts as a precursor for RNA, which is necessary for many cellular functions, such as protein production and gene control. Second, it has been related to the control of neurotransmitter synapses that are involved in mood, motivation, memory, and learning, such as dopamine and acetylcholine . Additionally, UMP-Disodium may promote mitochondrial function in the brain, support healthy brain cell membranes such as dendritic membranes, and enhance synaptic function. [R

Uridine plays a crucial role in boosting brain function by increasing the levels of a substance called phosphatidylcholine. This substance is essential for the proper functioning of brain cells and the connections between them, known as synapses. Uridine is like a key ingredient in a process called the Kennedy cycle or CDP-choline pathway, where it helps create phosphatidylcholine. This pathway also produces another important substance called phosphatidylethanolamine, which is vital for neurotransmission and building brain cell membranes. By assisting in these processes, uridine has the potential to improve brain function and synaptic activity. In this pathway, an enzyme called choline kinase uses uridine to transform choline into phosphocholine with the help ATP molecule. This conversion allows for more cellular choline to be used in creating phosphatidylcholine.[R]

Uridine Monophosphate Disodium Research

Numerous studies have been conducted on the potential application of Uridine monophosphate disodium . Below are some of the relevant findings on Uridine monophosphate disodium benefits :

Uridine Monophosphate Disodium as Cognitive Function Enhancer

It has been investigated whether uridine monophosphate disodium (UMP disodium) has any potential to improve cognitive function. According to studies, UMP disodium may increase learning and memory by boosting the level of the important neurotransmitter acetylcholine in the body. In older rats, UMP disodium has also been shown to encourage neurite outgrowth, which would add to its potential cognitive advantages. Additionally, UMP disodium might strengthen and reorganize synapses in the brain, which might aid in brain adaptation, learning, memory, and regrowth. Some users of UMP disodium have found relief from depression and pain in their nerves, and it may also support restful sleep. More research is required to validate these effects, and people with specific medical conditions shouldn’t use UMP disodium. [R] [R] [R]

Uridine Monophosphate Disodium as Sleep Quality Improver

Good sleep hygiene is crucial for supporting restful sleep, increasing daily alertness, and preventing the emergence of sleep disorders and issues. Uridine monophosphate disodium (UMP disodium) may aid to support healthy sleep patterns, according to some studies, despite the paucity of research on the substance’s effects on sleep quality. Some users of UMP disodium claim that it enhances their sleep quality. To substantiate these effects, additional research is required. [R] [R]

Studies conducted on rats have shown that uridine increased slow-wave or deep sleep, especially in situations where the rats were sleep-deprived. Slow-wave sleep is crucial for the brain’s recovery from daily activities. Therefore, it appears that one of the indirect ways in which Uridine Monophosphate supports cognitive function is by promoting restful and restorative sleep. [R]

Uridine monophosphate disodium as Nerve Pain Reducer

Some users of uridine monophosphate disodium (UMP disodium) have stated that it may help them with their nerve discomfort. According to studies, giving patients with painful conditions like diabetic neuropathy, back pain, and trauma-compressive disorders medications containing pyrimidine nucleotides, such as uridine triphosphate (UTP) and cytidine monophosphate (CMP), has been shown to be effective in reducing their pain’s intensity. Uridine, a part of RNA that may enhance brain function, lessen depression and nerve pain, and safeguard the heart, is found in UMP disodium. It is crucial to speak with a healthcare provider before using UMP disodium because further research is required to clarify its precise effects on nerve pain. [R] [R]

Uridine Monophosphate Disodium as Depression and Bipolar Disorder Reliever

By enhancing mitochondrial function and cell membrane health, uridine monophosphate disodium (UMP disodium) has been suggested to potentially treat depression and bipolar illness. UMP disodium was well tolerated by research participants and was related with a reduction in depressive symptoms in a trial of seven depressed teenagers with bipolar illness. Pyrimidine nucleosides are a class of chemicals that have the ability to affect energy metabolism and excitatory glutamatergic transmission in the brain, and this is how UMP disodium may function. It is crucial to speak with a healthcare provider before using UMP disodium because further study is required to clarify its precise effects on depression and bipolar disorder. [R] [R]

Uridine monophosphate disodium on Lung Diseases

There are currently few treatments for pulmonary fibrosis, which is a chronic condition that worsens over time. But in an animal model of pulmonary fibrosis, uridine monophosphate disodium (UMP disodium) has been demonstrated to exert anti-inflammatory and anti-fibrotic properties. UMP disodium prevented human neutrophils from producing reactive oxygen species, human lung epithelial cells from releasing pro-inflammatory cytokines, and primary lung fibroblasts from producing collagen and TGF-ß. It has been demonstrated that UMP disodium supplementation is safe and well tolerated in people, suggesting that this could be a potential therapeutic strategy for the management of fibrotic lung disorders. [R] [R]

Uridine Monophosphate Disodium on Alzheimer’s Disease 

Alzheimer’s disease is a neurodegenerative condition marked by the loss of brain connections and cognitive decline. Uridine monophosphate disodium (UMP disodium) has been investigated for its potential impact on Alzheimer’s disease. Although there is little clinical research to support the use of UMP disodium for enhancing cognitive function, it is present in some dietary interventions for Alzheimer’s disease, such as Souvenaid, which contains a special blend of nutrients intended to support brain connections. [R] [R] More research is required to fully comprehend the potential advantages and mechanisms of action of UMP disodium along with uridine dha stack, on Alzheimer’s disease.


The information presented here is for educational purposes only and should not be construed as medical advice.  Uridine monophosphate disodium is intended for laboratory research use only and is not intended to be considered as uridine supplement or dietary supplement.

Potential Side Effects

The following are some common side effects reported in studies and by users of Uridine monophosphate disodium: [R] [R]

  • Headaches
  • Nausea
  • Vomiting
  • Diarrhea
  • Abdominal cramps
  • Indigestion
  • Vivid dreams
  • Fever (at high doses)

Where Can I Buy  Uridine Monophosphate Disodium online? offers  Uridine monophosphate disodium powder for laboratory and research use only. Others also sell uridine monophosphate capsules

When buying  Uridine monophosphate disodium, it is important to choose a reputable market seller who provides quality products. At, customers can ensure each product is accompanied with a third-party-issued Certificate of Analysis showing the identification, purity, and concentration of our product.


The nucleotide uridine monophosphate takes essential factor for several biological functions. It is a significant part of ribonucleic acid (RNA) and is an ester of phosphoric acid and the nucleotide uridine. UMP disodium has been investigated for its potential to enhance cognition, as well as for its potential to enhance sleep, soothe nerve discomfort, and lessen lung disease symptoms. Additionally, preliminary study indicates that UMP disodium may lessen the symptoms of bipolar illness and depression by enhancing mitochondrial function and cell membrane health. Although most individuals generally believe UMP disodium to be safe when taken at the recommended doses, some potential adverse effects have been noted, albeit they are often small and temporary. More research is needed to fully understand the potential benefits and risks of UMP disodium.


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