Yohimbine HCl is a beneficial compound that has the potential to be utilized for treating erectile dysfunction and is believed to aid in weight loss. Derived from the bark of the Yohimbe tree (Pausinystalia yohimbe), an evergreen native to central and western Africa, yohimbine acts as the primary active ingredient. The historical use of Yohimbe bark in potentially promoting sexual well-being further adds to its significance.

Yohimbine HCl Product Details

Yohimbine HCl is a compound derived from the bark of the Yohimbe plant, scientifically known as Pausinystalia Yohimbe. It has gained attention for its potential effects on various aspects of human health. One notable area is its association with weight loss making it a potential fat-loss supplement.

The Yohimbe plant has a long history of potential traditional use in promoting sexual wellness, particularly in supporting healthy blood flow. Yohimbine HCl is considered one of the active ingredients responsible for these effects. By acting as an alpha-2 adrenoceptor antagonist, yohimbine HCl may help improve blood flow and circulation, which can potentilly have implications for sexual health and performance.

It is important to note that Yohimbine HCl is not an approved dietary supplement. Buy Yohimbine HCl for research purposes only.

Key Features of Yohimbine HCl High Potency for Sale

  • 98% Purity
  • 5g

Potential Benefits of Yohimbine HCl

Yohimbine HCl and Diabetes

Yohimbine HCl has shown potential benefits for test subjects with diabetes based on selected clinical studies. In a trial involving 50 diabetes patients, Yohimbine HCl demonstrated an ability to improve blood sugar management by increasing insulin levels. Similarly, Yohimbine therapy in diabetic rats resulted in reduced blood glucose levels and increased insulin production. [R]

However, it is crucial to emphasize that these findings are derived from a single clinical trial and animal studies. Yohimbine HCl is not one of the recommended prescription medications for diabetes. [R]

Yohimbine HCl and Fear

Yohimbine has been studied for its potential to reduce the fear response by increasing norepinephrine levels. Various research studies, conducted on both animals and humans, have provided insights into this area. Yohimbine has demonstrated a reduction in social anxiety and an elevation in mood in a study involving 40 individuals with psychiatric conditions, including depression. [R] [R] [R]

Yohimbine HCl and Memory

Yohimbine has been explored for its impact on memory, particularly its ability to increase norepinephrine levels. A study involving 36 test subjects demonstrated that Yohimbine could enhance long-term memory. However, it is worth noting that a study on rats indicated that Yohimbine might impair working memory. [R] [R]

While these findings provide preliminary evidence of potential memory-related benefits, further clinical studies are needed to confirm and expand upon these findings. [R] [R]

Yohimbine HCl and Weight Loss

Weight loss is a common area of research, leading to a continuous search for effective fat-burning compounds that impact fat cells. Yohimbine HCl has been the focus of studies examining its potential to enhance weight loss efforts. [R] [R] [R]

In a controlled study involving 20 test subjects, the administration of Yohimbine resulted in a significant reduction of body fat levels, from 9.3% to 7.1%. Additionally, three short clinical investigations have suggested that taking Yohimbine prior to exercise or during fasting can enhance fat breakdown. Furthermore, an animal study has indicated that Yohimbine may also possess appetite-suppressing properties. [R] [R] [R]

Yohimbine HCl and Blood Clotting

Excessive blood clotting can lead to serious health issues such as stroke, heart attack, or kidney failure. Yohimbine HCl has shown promise in minimizing blood clotting by inhibiting alpha-2 adrenoceptors, as indicated in several clinical trials. Additionally, Yohimbine can convert epinephrine to norepinephrine, further influencing blood coagulation. [R] [R] [R]

Yohimbine HCl and Dry Mouth Syndrome

In addition to its potential as a weight loss aid, Yohimbine HCl has also been investigated for its effects on dry mouth syndrome. A small research group of 20 test subjects showed that Yohimbine HCl could increase saliva production. Furthermore, another study found that Yohimbine HCl increased salivary flow by 3.5 times in 10 individuals experiencing dry mouth due to antidepressant medication. Interestingly, Yohimbine HCl has also been observed to stimulate saliva production in dogs. [R] [R]

How It Works

Yohimbine HCl exerts its mechanism of action by blocking alpha-1 and alpha-2 adrenoceptors, leading to specific physiological effects. This blocking activity results in the elevation of adrenaline and dopamine levels, while simultaneously reducing serotonin levels. By targeting these receptors, several outcomes can be expected.

Firstly, the blocking of alpha-1 and alpha-2 adrenoceptors by yohimbine leads to an increase in blood pressure. This effect is a consequence of the disrupted regulation of these receptors, which play a role in modulating blood vessel constriction and dilation.

Secondly, Yohimbine’s action on adrenoceptors triggers the release of insulin. Insulin is a hormone involved in regulating blood sugar levels, and its release can be influenced by the activation or blockade of certain receptors. Yohimbine’s ability to stimulate insulin release can have implications for glucose metabolism.

Lastly, Yohimbine has the potential to inhibit various dopamine and serotonin receptors. Specifically, it targets dopamine-2 and dopamine-3 receptors (D2 and D3), as well as serotonin-1B, serotonin-1D, serotonin-2A, and serotonin-2B receptors (5-HT1B, 5-HT1D, 5-HT2A, and 5-HT2B).

By interfering with the functioning of these receptors, Yohimbine may potentially modulate the neurotransmitter balance in the brain, potentially impacting mood, behavior, and various physiological processes regulated by dopamine and serotonin.


When purchasing Yohimbine HCl online, it is critical to prioritize label reading to ensure that the laboratory subjects do not exceed the recommended daily intake outlined in the supplement facts serving size. This precaution is especially important given the prevalence of mislabeled brands among mainstream dietary supplements, where the actual amount of Yohimbine in the products is unknown. Surprisingly, out of the 49 Yohimbine supplements investigated in a study, only two were found to have accurate labeling and reliable information.

Furthermore, research comparing calls made to the California Poison Control System between 2000 and 2006 shed light on the potential adverse effects associated with Yohimbine HCl and other related chemicals. Reported cases indicated that the research compound could lead to stomach problems, tachycardia (fast heartbeat), anxiety, and elevated blood pressure.

Potential Side Effects

The use of Yohimbine HCl High Potency should be approached with caution due to potential safety concerns and side effects. While Yohimbine HCl has been studied for various purposes, it is important to note adverse reactions occur in some cases where test subjects exceed recommended daily intake. Common side effects include increased heart rate, elevated blood pressure, anxiety, gastrointestinal discomfort, and headaches. Additionally, Yohimbine HCl may interact with certain medications, particularly those that affect blood pressure or mental health.


In conclusion, Yohimbine HCl High Potency offers potential benefits, but it is crucial to approach its usage with caution and careful consideration. Yohimbine HCl has been associated with potential benefits such as addressing high blood pressure, promoting fat cell metabolism, and supporting sexual wellness. However, it is essential not to rely solely on Yohimbine HCl and to adopt a comprehensive approach to overall health and well-being.

Adverse reactions, including heart palpitations, may occur, particularly in individuals with psychiatric diseases or seizure disorders. When considering Yohimbine HCl High Potency supplementation, it is essential to read labels and choose products that are processed with high-quality ingredients and manufactured in GMP-compliant facilities.

Storing Yohimbine HCl High Potency in a cool, dry place is recommended to maintain its potency and purity. Additionally, it is important to be mindful of other ingredients, such as caffeine, present in some formulations, especially for those sensitive to its stimulating effects. Customer reviews and feedback can provide valuable insights into the efficacy and suitability of specific Yohimbine HCl High Potency products.

When purchasing Yohimbine HCL, it is critical to select a trusted source that offers high-quality items. At, each product is accompanied by a third-party-issued Certificate of Analysis demonstrating the product’s identity, purity, and concentration.

RCD. Bio also sells Yohimbine HCL in capsule and powder form for research purposes.

Now bear in mind that a powdered form allows for the use of supposed beneficial and effective dosages of the compound. A powder blend, unlike capsules, does not have a minimum or maximum space capacity. However, remember that the larger the powder dosage, the more expensive the product.


Please take note of the scientific applications of this product and carefully read our Terms and Conditions before making a purchase from By completing your order and submitting payment, you agree to abide by our Terms and Conditions. Please be aware that the product packaging may differ slightly from the images displayed on our website.

If for any reason you are not completely satisfied with the product you receive, please contact us at [email protected]. Our team is dedicated to ensuring customer satisfaction and will be happy to assist you.

PLEASE NOTE: All products offered by are strictly intended for laboratory and research purposes only. They are not intended for use on animals or humans.